Document Detail


Quorum sensing enhances the stress response in Vibrio cholerae.
MedLine Citation:
PMID:  17434996     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Vibrio cholerae lives in aquatic environments and causes cholera. Here, we show that quorum sensing enhances V. cholerae viability under certain stress conditions by upregulating the expression of RpoS, and this regulation acts through HapR, suggesting that a quorum-sensing-enhanced stress response plays a role in V. cholerae environmental survival.
Authors:
Adam Joelsson; Biao Kan; Jun Zhu
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2007-04-13
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  73     ISSN:  0099-2240     ISO Abbreviation:  Appl. Environ. Microbiol.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-29     Completed Date:  2007-07-31     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3742-6     Citation Subset:  IM    
Affiliation:
Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / pharmacology
Artificial Gene Fusion
Bacterial Proteins / biosynthesis,  physiology
Gene Expression Regulation, Bacterial*
Genes, Reporter
Hydrogen Peroxide / pharmacology
Microbial Viability*
Oxidative Stress*
Quorum Sensing / physiology*
Sigma Factor / biosynthesis,  physiology
Up-Regulation
Vibrio cholerae / genetics,  physiology*
beta-Galactosidase / analysis,  genetics
Grant Support
ID/Acronym/Agency:
K22 AI060715/AI/NIAID NIH HHS; R01 AI072479/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Bacterial Proteins; 0/Sigma Factor; 0/sigma factor KatF protein, Bacteria; 7722-84-1/Hydrogen Peroxide; EC 3.2.1.23/beta-Galactosidase
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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