Document Detail


Quantum dots as contrast agents for in vivo tumor imaging: progress and issues.
MedLine Citation:
PMID:  20658228     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Quantum dots (QDs) have shown promise as imaging agents in cancer, heart disease, and gene therapy research. This review focuses on the design of QDs, and modification using peptides and proteins for mediated targeting of tissues for fluorescence imaging of tumors in vivo. Recent examples from the literature are used to illustrate the potential of QDs as effective imaging agents. The distribution and ultimate fate of QDs in vivo is considered, and considerations of designs that minimize potential toxicity are presented.
Authors:
Anthony J Tavares; Lori Chong; Eleonora Petryayeva; W Russ Algar; Ulrich J Krull
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Publication Detail:
Type:  Journal Article     Date:  2010-07-25
Journal Detail:
Title:  Analytical and bioanalytical chemistry     Volume:  399     ISSN:  1618-2650     ISO Abbreviation:  Anal Bioanal Chem     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101134327     Medline TA:  Anal Bioanal Chem     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  2331-42     Citation Subset:  IM    
Affiliation:
Chemical Sensors Group Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, ON, L5L 1C6, Canada.
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