| Quantitative thermal sensory testing -- value of testing for both cold and warm sensation detection in evaluation of small fiber neuropathy. | |
| | |
MedLine Citation:
|
PMID: 16202822 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Small fiber neuropathy is a common neurological disorder, often missed or ignored by physicians, since examination and routine nerve conduction studies are usually normal in this condition. Many methods including quantitative thermal sensory testing are currently being used for early detection of this condition, so as to enable timely investigation and treatment. This study was conducted to assess the yield of quantitative thermal sensory testing in diagnosis of small fiber neuropathy. MATERIAL AND METHODS: We included patients presenting with history suggestive of positive and/or negative sensory symptoms, with normal examination findings, clinically suggestive of small fiber neuropathy, with normal or minimally abnormal routine nerve conduction studies. These patients were subjected to quantitative thermal sensory testing using a Medoc TSA-II Neurosensory analyser at two sites and for two modalities. QST data were compared with those in 120 normal healthy controls. RESULTS: Twenty-five patients (16 males, 9 females) with mean age 46.8+/-16.6 years (range: 21-75 years) were included in the study. The mean duration of symptoms was 1.6+/-1.6 years (range: 3 months-6 years). Eighteen patients (72%) had abnormal thresholds in at least one modality. Thermal thresholds were normal in 7 out of the 25 patients. CONCLUSION: This study demonstrates that quantitative thermal sensory testing is a fairly sensitive method for detection of small fiber neuropathy especially in patients with normal routine nerve conduction studies. |
| | |
Authors:
|
Garima Shukla; Manvir Bhatia; Madhuri Behari |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical neurology and neurosurgery Volume: 107 ISSN: 0303-8467 ISO Abbreviation: Clin Neurol Neurosurg Publication Date: 2005 Oct |
Date Detail:
|
Created Date: 2005-10-05 Completed Date: 2006-01-06 Revised Date: 2009-10-14 |
Medline Journal Info:
|
Nlm Unique ID: 7502039 Medline TA: Clin Neurol Neurosurg Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 486-90 Citation Subset: IM |
Affiliation:
|
Department of Neurology, All India Institute of Medical Sciences, New Delhi 110029, India. garimashukla@hotmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Female Humans Male Middle Aged Nerve Fibers / physiology* Neural Conduction / physiology Paresthesia / diagnosis, physiopathology Peripheral Nerves / physiopathology Peripheral Nervous System Diseases / diagnosis* Sensation Disorders / diagnosis*, physiopathology Sensory Thresholds / physiology Signal Processing, Computer-Assisted Temperature Thermoreceptors / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Central motor conduction in cervical dystonia with cervical spondylotic myelopathy.
Next Document: Factors influencing outcome in Guillain-Barré Syndrome: comparison of plasma adsorption against oth...