Document Detail


Quantitative thallium-201 myocardial exercise scintigraphy in normal subjects and patients with normal coronary arteries.
MedLine Citation:
PMID:  2311601     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Quantitative thallium-201 myocardial exercise scintigraphy was tested in two patient populations representing alternative standards for cardiac normality: group I comprised 18 male uncatheterized patients with a low likelihood of coronary artery disease (CAD); group II contained 41 patients with normal coronary arteriograms. Group I patients were younger, they achieved a higher rate-pressure product than group II patients; all had normal findings by physical examination and electrocardiography at rest and exercise. Group II patients comprised 21 females, 11 patients showed abnormal electrocardiography at rest, and five patients showed ischemic ST depression during exercise. Twelve patients had signs of minimal CAD. Twelve patients revealed abnormal visual and quantitative thallium findings, three of these patients had minimal CAD. Profiles of uptake and washout of thallium-201 were derived from both patient groups, and compared with normal limits developed by Maddahi et al. Furthermore, low likelihood and angiographically normal patients may differ substantially, and both sets of normal patients should be considered when establishing criteria for abnormality in exercise thallium imaging. When commercial software containing normal limits for quantitative analysis of exercise thallium-201 imaging is used in clinical practice, it is mandatory to compare these with normal limits of uptake and washout of thallium-201, derived from the less heterogeneous group of low-likelihood subjects, which should be used in selecting a normal population to define normality.
Authors:
M G Niemeyer; G J Laarman; S Lelbach; M J Cramer; L T Go; J F Verzijlbergen; E E van der Wall; A H Zwinderman; C A Ascoop; E K Pauwels
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of radiology     Volume:  10     ISSN:  0720-048X     ISO Abbreviation:  Eur J Radiol     Publication Date:    1990 Jan-Feb
Date Detail:
Created Date:  1990-04-20     Completed Date:  1990-04-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  19-27     Citation Subset:  IM    
Affiliation:
Department of Diagnostic Radiology, University Hospital, Leiden, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Adult
Coronary Disease / radionuclide imaging*
Electrocardiography
Exercise / physiology
Exercise Test
Female
Heart / radionuclide imaging*
Humans
Image Processing, Computer-Assisted*
Male
Middle Aged
Reference Values
Thallium Radioisotopes / diagnostic use*
Chemical
Reg. No./Substance:
0/Thallium Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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