Document Detail

Quantitative regional cerebral blood flow measurement techniques improve noninvasive detection of cerebrovascular vasospasm after aneurysmal subarachnoid hemorrhage.
MedLine Citation:
PMID:  11641584     Owner:  NLM     Status:  MEDLINE    
Adequate therapy of vasospasm (VS) in patients suffering from aneurysmal subarachnoid hemorrhage critically depends upon early and reliable diagnosis of cerebral hypoperfusion. The objective of the present study was to evaluate the usefulness of quantitative regional blood flow (rCBF) analysis as an adjunct in noninvasive prediction of VS. Therefore, 33 transcranial Doppler sonography (TCD) studies assuming cerebrovascular VS (TCD flow velocity >120 cm/s) were followed by (s)Xe/CT and cerebral panangiography (PA). TCD plus (s)Xe/CT significantly increased the predictability of VS from 34 to 91%, proving that a combination of TCD and rCBF studies improves the noninvasive detection of VS and might help to prevent unnecessary angiographic examinations.
P Horn; P Vajkoczy; C Bauhuf; E Münch; C Poeckler-Schoeniger; P Schmiedek
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Cerebrovascular diseases (Basel, Switzerland)     Volume:  12     ISSN:  1015-9770     ISO Abbreviation:  Cerebrovasc. Dis.     Publication Date:  2001  
Date Detail:
Created Date:  2001-10-19     Completed Date:  2002-01-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9100851     Medline TA:  Cerebrovasc Dis     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  197-202     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Department of Neurosurgery, University Hospital Mannheim, Mannheim, Germany.
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MeSH Terms
Cerebral Angiography
Cerebrovascular Circulation*
Drug Stability
Intracranial Aneurysm / complications*
Middle Aged
Subarachnoid Hemorrhage / complications*
Tomography, X-Ray Computed
Ultrasonography, Doppler, Transcranial
Vasospasm, Intracranial / diagnosis*,  etiology*
Xenon / diagnostic use
Reg. No./Substance:

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