Document Detail


Quantitative polyphosphate-induced "prebiotic" peptide formation in H2O by addition of certain azoles and ions.
MedLine Citation:
PMID:  6442994     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aqueous solutions of 0.1 M amino acid and 0.1 M trimetaphosphate maintained at chosen pH values between 8.0 and 10.5 and at room temperature in the presence of imidazole or 1,2,4-triazole give rise after a few days to the corresponding peptides. Yields are highest when the pH is adjusted with concentrated NaOH or KOH instead of ammonia; in some cases glycine is quantitatively transformed within 10-15 days into peptides, mainly di-and tripeptides.
Authors:
J Rabinowitz; A Hampaï
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of molecular evolution     Volume:  21     ISSN:  0022-2844     ISO Abbreviation:  J. Mol. Evol.     Publication Date:    1984-1985
Date Detail:
Created Date:  1985-08-09     Completed Date:  1985-08-09     Revised Date:  2006-07-19    
Medline Journal Info:
Nlm Unique ID:  0360051     Medline TA:  J Mol Evol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  199-201     Citation Subset:  IM; S    
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MeSH Terms
Descriptor/Qualifier:
Azoles
Biogenesis*
Catalysis
Hydrogen-Ion Concentration
Ions
Peptides*
Polyphosphates*
Water
Chemical
Reg. No./Substance:
0/Azoles; 0/Ions; 0/Peptides; 0/Polyphosphates; 7732-18-5/Water

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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