Document Detail


Quantitative oxygen measurements before and after intravascular guanethidine blocks.
MedLine Citation:
PMID:  6886339     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 11 patients oxygen pressure was measured transcutaneously before and after treatment with regional intravascular sympathetic blocks in extremities with pain, impairment of function, and/or dystrophy. In 50 normal individuals PO2 levels were determined in the hand. All patients showed lower than normal values before treatment. Subjective complaints were registered by means of a questionnaire before and after treatment. Improvement of PO2 levels was observed after treatment in eight out of 11 patients while complaints disappeared. Three out of 11 patients showed no improvement of PO2 levels or any lessening of complaints. Control PO2 values in the contralateral limbs stayed on the same level as before treatment in all patients. From the results in this article it can be stated that TcPO2 measurements seem to be helpful in (1) evaluating the pretreatment microvascular state of the affected limb and (2) judging the efficacy of the block.
Authors:
G J Sonneveld; J C van der Meulen; A R Smith
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of hand surgery     Volume:  8     ISSN:  0363-5023     ISO Abbreviation:  J Hand Surg Am     Publication Date:  1983 Jul 
Date Detail:
Created Date:  1983-10-08     Completed Date:  1983-10-08     Revised Date:  2009-06-08    
Medline Journal Info:
Nlm Unique ID:  7609631     Medline TA:  J Hand Surg Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  435-42     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Autonomic Nerve Block / methods*
Extremities / blood supply*
Female
Guanethidine / pharmacology*,  therapeutic use
Humans
Male
Middle Aged
Oxygen / analysis
Oxygen Consumption / drug effects*
Pain / therapy*
Chemical
Reg. No./Substance:
55-65-2/Guanethidine; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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