Document Detail


Quantitative modeling of perception and production of time intervals.
MedLine Citation:
PMID:  11731535     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The accurate perception/production of durations in the seconds and minutes range is important in a number of everyday activities, but the lack of direct experimental evidence on the neural circuits that could be involved has precluded the detailed elucidation of the underlying physiological mechanisms. We show, using a basic biophysical model of a timekeeping system and experimental data on time intervals produced or estimated under different conditions, that experimental values, variability, and distributions can be quantitatively explained in terms of a background synaptic activity such as that generated by attention. The model provides a plausible neural substrate for encoding time intervals, and the findings suggest how it may interplay at the single neuron level with the attentional system, to elaborate a subjective representation of the elapsing time.
Authors:
M Migliore; L Messineo; M Cardaci; G F Ayala
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of neurophysiology     Volume:  86     ISSN:  0022-3077     ISO Abbreviation:  J. Neurophysiol.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-03     Completed Date:  2002-01-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375404     Medline TA:  J Neurophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2754-60     Citation Subset:  IM    
Affiliation:
Section of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520-8001, USA. migliore@iaif.pa.cnr.it
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MeSH Terms
Descriptor/Qualifier:
Humans
Models, Neurological
Neural Conduction / physiology
Neural Networks (Computer)
Neurons / physiology
Prospective Studies
Synapses / physiology
Time Perception / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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