Document Detail

Quantitative measurement of blood-brain barrier permeability using perfusion-CT in extra-axial brain tumors.
MedLine Citation:
PMID:  16840958     Owner:  NLM     Status:  MEDLINE    
Non-invasive assessment of vascular permeability is of main importance in the diagnosis, treatment and follow-up of intracranial tumors. Perfusion-CT is one of the imaging options available, which affords quantitative assessment of cerebral blood volume and blood-brain barrier permeability. Herein we report two cases of extra-axial tumors studied with perfusion-CT. Comparison with perfusion-MRI was available in one case. High permeability values, as measured by perfusion-CT, reflected the absence of blood-brain barrier in these extra-axial tumors.
A Cianfoni; S Cha; W G Bradley; W P Dillon; M Wintermark
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neuroradiology. Journal de neuroradiologie     Volume:  33     ISSN:  0150-9861     ISO Abbreviation:  J Neuroradiol     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-07-14     Completed Date:  2006-09-12     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  7705086     Medline TA:  J Neuroradiol     Country:  France    
Other Details:
Languages:  eng     Pagination:  164-8     Citation Subset:  IM    
Universita Cattolica del Sacro Cuore (UCSC), Policlinico Agostino Gemelli, Department of Radiology, Roma, Italy.
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MeSH Terms
Aged, 80 and over
Blood-Brain Barrier*
Brain Neoplasms / radiography*,  secondary
Cerebrovascular Circulation
Magnetic Resonance Imaging
Meningioma / radiography*
Middle Aged
Tomography, X-Ray Computed / methods*
Comment In:
J Neuroradiol. 2007 Mar;34(1):72; author reply 72-3   [PMID:  17320175 ]

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