| Quantitative left ventricular contractility analysis under stress: a new practical approach in follow-up of hypertensive patients. | |
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MedLine Citation:
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PMID: 21107433 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Excessive sympathetic activity and stress-induced left ventricular (LV) hypercontractility have been described in hypertensive LV hypertrophy. Recent quantitative data have shown that hypertensive LV hypertrophy is associated with preserved global LV function. However, progression of uncontrolled hypertension have detrimental effects on both the ejection fraction (EF) and LV contractile response to stress. Hypertensive LV hypertrophy has some common characteristics, including preserved global LV systolic function and LV volume with heart failure with preserved EF (HFPEF), which makes it difficult to differentiate between the two conditions at rest. Studies suggest that adopting an efficient antihypertensive therapy regimen may positively effect on the LV contractile capability in patients with long-standing hypertension. Evaluation of quantitative LV contractility under stress may be beneficial to differentiate between the hypertensive LV hypertrophy and HFPEF. It may also assist in developing a more effective modality in medical management of patients with hypertensive heart disease. |
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Authors:
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F Yalçin; H Yalçin; N Küçükler; T P Abraham |
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Publication Detail:
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Type: Journal Article Date: 2010-11-25 |
Journal Detail:
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Title: Journal of human hypertension Volume: 25 ISSN: 1476-5527 ISO Abbreviation: J Hum Hypertens Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-09-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8811625 Medline TA: J Hum Hypertens Country: England |
Other Details:
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Languages: eng Pagination: 578-84 Citation Subset: IM |
Affiliation:
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Divisions of Cardiology and Nuclear Medicine, Department of Medicine, Johns Hopkins Medical Institutions, Cardiovascular Imaging Center, Baltimore, MD, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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