| Quantitative hemodynamic studies in moyamoya disease: a review. | |
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MedLine Citation:
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PMID: 19335131 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Moyamoya disease is characterized by a chronic stenoocclusive vasculopathy affecting the terminal internal carotid arteries. The clinical presentation and outcome of moyamoya disease remain varied based on angiographic studies alone, and much work has been done to study cerebral hemodynamics in this group of patients. The ability to measure cerebral blood flow (CBF) accurately continues to improve with time, and with it a better understanding of the pathophysiological mechanisms in patients with moyamoya disease. The main imaging techniques used to evaluate cerebral hemodynamics include PET, SPECT, xenon-enhanced CT, dynamic perfusion CT, MR imaging with dynamic susceptibility contrast and with arterial spin labeling, and Doppler ultrasonography. More invasive techniques include intraoperative ultrasonography. The authors review the current knowledge of CBF in this group of patients and the role each main quantitative method has played in evaluating them, both in the disease state and after surgical intervention. |
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Authors:
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Marco Lee; Greg Zaharchuk; Raphael Guzman; Achal Achrol; Teresa Bell-Stephens; Gary K Steinberg |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Neurosurgical focus Volume: 26 ISSN: 1092-0684 ISO Abbreviation: Neurosurg Focus Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-04-01 Completed Date: 2009-07-14 Revised Date: 2010-09-23 |
Medline Journal Info:
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Nlm Unique ID: 100896471 Medline TA: Neurosurg Focus Country: United States |
Other Details:
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Languages: eng Pagination: E5 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Stanford Stroke Center, Stanford, California, USA. marcolee@stanford.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Angiography
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methods,
trends Cerebral Arteries / physiopathology*, radiography, ultrasonography Cerebrovascular Circulation / physiology* Diagnostic Imaging / methods*, trends Hemodynamics / physiology* Humans Moyamoya Disease / diagnosis*, physiopathology* Radioisotopes / diagnostic use Tomography, X-Ray Computed / methods, trends Ultrasonography / methods, trends |
| Grant Support | |
ID/Acronym/Agency:
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R01 NS066506-02/NS/NINDS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Radioisotopes |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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