Document Detail

Quantitative evaluation of mitral regurgitation with ultrafast CT.
MedLine Citation:
PMID:  8126274     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To quantify cardiac valvular regurgitation, ultrafast CT was performed in 44 patients (including 27 patients with mitral regurgitation). MATERIALS AND METHODS: Stroke volume of the left ventricle was calculated by modified Simpson's rule with cine mode scanning of ultrafast CT, and ventricular output was measured as the product of stroke volume and heart rate. Cardiac output was calculated in the ascending aorta by the formula of the indicator dilution method with flow mode scanning of ultrafast CT. The difference between the left ventricular output and cardiac output was defined as "mitral regurgitant volume." Left ventriculography was also performed at the same time, to estimate the degree of mitral regurgitation according to Sellers' classification. RESULTS: There was significant correlation between regurgitant fraction, standardized regurgitant volume, and grade of mitral regurgitation estimated by left ventriculography. CONCLUSION: CT can measure mitral regurgitant volume by the combination of volumetry and indicator dilution method.
T Kaminaga; H Naito; M Takamiya; T Nishimura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  18     ISSN:  0363-8715     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    1994 Mar-Apr
Date Detail:
Created Date:  1994-04-11     Completed Date:  1994-04-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  239-42     Citation Subset:  IM    
Department of Tracer Kinetics, Osaka University Medical School, Japan.
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MeSH Terms
Cardiac Output
Contrast Media
Evaluation Studies as Topic
Heart Rate
Heart Ventricles / radiography
Indicator Dilution Techniques
Middle Aged
Mitral Valve Insufficiency / radiography*
Pulmonary Valve Insufficiency / radiography
Stroke Volume
Tomography, X-Ray Computed / methods*
Tricuspid Valve Insufficiency / radiography
Ventricular Function, Left
Reg. No./Substance:
0/Contrast Media

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