Document Detail


Quantitative evaluation of cerebral vascular permeability using multi-slice dynamic CT.
MedLine Citation:
PMID:  14753404     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We developed a method to measure regional permeability of cerebral capillary vessels, extracellular fluid space volume, and vascular bed volume using multi-slice dynamic CT with iodinated contrast medium. We implemented the method as a novel software "BBB study", and evaluated it in four cases of brain tumor. The examination time was about 20 minutes, and the resulting functional maps had quality sufficient to distinguish area of irregular permeability enhancement.
Authors:
K Nambu; T Nariai; T Terada
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurochirurgica. Supplement     Volume:  86     ISSN:  0065-1419     ISO Abbreviation:  Acta Neurochir. Suppl.     Publication Date:  2003  
Date Detail:
Created Date:  2004-02-02     Completed Date:  2004-03-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100962752     Medline TA:  Acta Neurochir Suppl     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  53-5     Citation Subset:  IM    
Affiliation:
Medical Engineering Research & Development Center, Medical Systems Company, TOSHIBA Corporation, Tochigi, Japan. nambu@mel.nasu.toshiba.co.jp
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MeSH Terms
Descriptor/Qualifier:
Adenoma / physiopathology,  radiography*
Brain Neoplasms / physiopathology,  radiography*
Capillary Permeability
Contrast Media
Extracellular Space / metabolism,  radiography
Glioblastoma / physiopathology,  radiography*
Humans
Pituitary Neoplasms / physiopathology,  radiography*
Tomography, X-Ray Computed* / methods
Chemical
Reg. No./Substance:
0/Contrast Media

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