| Quantitative estimation of minor conductive hearing loss with distortion product otoacoustic emissions in the guinea pig. | |
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MedLine Citation:
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PMID: 20968357 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Subclinical conductive hearing losses (CHLs) can affect otoacoustic emissions and therefore limit their potential in the assessment of the cochlear function. Theoretical considerations to estimate a minor CHL from DPOAE measurements [Kummer et al. (2006). HNO 54, 457-467] are evaluated experimentally. They are based on the fact, that the level difference of the stimulus tones L(1) and L(2) for optimal excitation of the inner ear is given by L(1)=aL(2)+b. A CHL is presumed to attenuate both L(1) and L(2) to the same extent such that excitation of the inner ear is no longer optimal. From the change of L(1) that is necessary to restore optimal excitation of the inner ear and thus to produce maximal DPOAE levels, the CHL can be estimated. In 10 guinea pig ears an experimental CHL was produced, quantified by determination of compound action potential (CAP) thresholds at 8 kHz (CHL(CAP)) and estimated from DPOAE measurements at 8 kHz (CHL(DPOAE)). CHLs up to 12 dB could be assessed. CHL(DPOAE) correlated well with CHL(CAP) (R=0.741, p=0.0142). Mean difference between CHL(DPOAE) and CHL(CAP) was 4.2±2.6 dB. Estimation of minor CHL from DPOAE measurements might help to increase the diagnostic value of DPOAEs. |
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Authors:
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Bernhard Olzowy; Christoph Deppe; Warangkana Arpornchayanon; Martin Canis; Sebastian Strieth; Peter Kummer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of the Acoustical Society of America Volume: 128 ISSN: 1520-8524 ISO Abbreviation: J. Acoust. Soc. Am. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7503051 Medline TA: J Acoust Soc Am Country: United States |
Other Details:
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Languages: eng Pagination: 1845-52 Citation Subset: IM |
Affiliation:
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Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilians University of Munich Medical Center, Marchioninistr. 15, 81377 Munich, Germany. bernhard.olzowy@med.uni-muenchen.de |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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