Document Detail


Quantitative changes of tropomyosin synthesis in RSV-transformed mammalian cells in comparison with normal fibroblasts.
MedLine Citation:
PMID:  6298645     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Protein profiles of three tumor mammalian cell lines and three control cell lines were analyzed by two-dimensional gel electrophoresis. Comparison of the cells labeled metabolically with 35S-methionine has revealed obvious differences in an area of molecular weights 34 000--36 000 daltons and pH 4.5-5.0. Two spots have been proposed to be alpha- and beta-tropomyosin subunits. Their synthesis decreases after cell transformation.
Authors:
M Urbancíková; M Grófová
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neoplasma     Volume:  29     ISSN:  0028-2685     ISO Abbreviation:  Neoplasma     Publication Date:  1982  
Date Detail:
Created Date:  1983-04-15     Completed Date:  1983-04-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0377266     Medline TA:  Neoplasma     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  655-60     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Avian Sarcoma Viruses
Cell Line
Cell Transformation, Neoplastic*
Fibroblasts / metabolism
Mice
Mice, Inbred C57BL
Molecular Weight
Rats
Rats, Inbred Strains
Sarcoma, Avian / metabolism*
Tropomyosin / biosynthesis*
Chemical
Reg. No./Substance:
0/Tropomyosin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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