| Quantitative changes in the digestive gland cells of the snail Helix aspersa after exposure to the fungicide copper oxychloride. | |
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MedLine Citation:
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PMID: 15482839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study investigated the relationship between accumulated copper in the digestive gland of Helix aspersa, after exposure to the fungicide copper oxychloride, and quantitative changes in the digestive gland cells of this snail. Snails were exposed to 80 and 240 microg g(-1) copper oxychloride for 6 weeks. Histological sections of digestive glands were analyzed by means of computer-assisted image analysis. Results indicate that copper is strongly accumulated in the digestive gland and that this organ is the main site of copper accumulation in the snail body. Also, as a result of copper accumulation in the digestive gland, measurable changes in epithelium cell height and area of this organ occur. In the case of cell height, these changes are dose-related. It is concluded that changes in digestive gland cells, as a result of copper oxychloride exposure, may possibly serve as biomarkers of exposure to this fungicide. |
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Authors:
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R G Snyman; A J Reinecke; S A Reinecke |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Ecotoxicology and environmental safety Volume: 60 ISSN: 0147-6513 ISO Abbreviation: Ecotoxicol. Environ. Saf. Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2004-10-14 Completed Date: 2005-01-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7805381 Medline TA: Ecotoxicol Environ Saf Country: United States |
Other Details:
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Languages: eng Pagination: 47-52 Citation Subset: IM |
Affiliation:
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Department of Zoology, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa. snymanr@ctech.ac.za |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Copper / pharmacokinetics*, poisoning* Digestive System / pathology* Environmental Exposure* Exocrine Glands Helix (Snails) / physiology* Tissue Distribution Water Pollutants, Chemical / poisoning* |
| Chemical | |
Reg. No./Substance:
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0/Water Pollutants, Chemical; 1332-65-6/copper oxychloride; 7440-50-8/Copper |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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