Document Detail


Quantitative bacteriology of tonsils removed from children with tonsillitis hypertrophy and recurrent tonsillitis with and without hypertrophy.
MedLine Citation:
PMID:  7639475     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aerobic and anaerobic bacterial species and their numbers were studied in tonsillar specimens from children who had undergone elective tonsillectomy: 6 patients with recurrent tonsillitis (RT), 9 with recurrent tonsillitis with hypertrophy (RTH), and 8 with obstructive tonsillar hypertrophy (OTH). Mixed flora were present in all tonsils, yielding an average of 6.7 isolates (5.6 aerobic or facultative and 1.1 anaerobic bacteria). The highest recovery rate of organisms per tonsil was in patients with OTH (7.7 per tonsil), compared to 6.3 per tonsil in RT and 5.9 per tonsil in RTH. The predominant aerobic and facultative organisms were Haemophilus influenzae (22 isolates), Neisseria sp (16), Staphylococcus aureus (14), and Eikenella corrodens (14), and the predominant anaerobic bacteria were Fusobacterium sp (8), Bacteroides sp (7), and Prevotella melaninogenica (5). The number of bacteria per gram of tonsillar tissue varied between 10(4) and 10(8). A higher concentration of S aureus and H influenzae was found in hypertrophic tonsils (RTH and OTH) as compared to RT. These findings suggest the presence of an increased bacterial load and supports an etiologic role for H influenzae and S aureus in hypertrophic tonsils with and without inflammation (RTH and OTH). Further studies to elucidate the effect of selective antimicrobial therapy directed at these organisms may offer an alternative management of hypertrophic tonsils.
Authors:
J J Kuhn; I Brook; C L Waters; L W Church; D A Bianchi; D H Thompson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of otology, rhinology, and laryngology     Volume:  104     ISSN:  0003-4894     ISO Abbreviation:  Ann. Otol. Rhinol. Laryngol.     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-09-13     Completed Date:  1995-09-13     Revised Date:  2006-05-15    
Medline Journal Info:
Nlm Unique ID:  0407300     Medline TA:  Ann Otol Rhinol Laryngol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  646-52     Citation Subset:  AIM; IM    
Affiliation:
Department of Otolaryngology, Naval Hospital, Bethesda, Maryland, USA.
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MeSH Terms
Descriptor/Qualifier:
Bacterial Infections / microbiology*,  pathology,  surgery
Case-Control Studies
Child
Child, Preschool
Colony Count, Microbial
Female
Humans
Hypertrophy
Male
Recurrence
Severity of Illness Index
Tonsillectomy
Tonsillitis / microbiology*,  pathology,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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