Document Detail

Quantitative assessment of myocardial enhancement with iodinated contrast medium in patients with ischemic heart disease by using ultrafast x-ray computed tomography.
MedLine Citation:
PMID:  1607259     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND RATIONALE: The authors report the quantitation of myocardial enhancement using iodinated contrast medium in patients with ischemic heart disease. Twenty-eight patients with chronic ischemic heart disease and 11 controls were examined by ultrafast computed tomography (CT) using 100-msecond scans. METHODS: The authors analyzed M/L (ratio of post-contrast incremental increases in the left ventricular myocardial and luminal CT number) in early and late phases after contrast injection. RESULTS: In controls, mean values of early and late M/L were 30% and 51%, respectively. In infarcted or severely ischemic segments, early M/Ls (19%, 16%) were significantly small (P less than .001), whereas late M/Ls (90%, 63%) were higher (P less than .001, .01) than controls. Segments with infarction or severe ischemia were differentiated from mild or nonsignificant ischemia by using this parameter (sensitivity, 99%; specificity, 88%). CONCLUSIONS: M/L is useful for detection of the ischemic myocardium.
H Naito; H Saito; M Takamiya; S Hamada; N Yamada; S Imakita; M Ohta; K Kimura; S Tamura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Investigative radiology     Volume:  27     ISSN:  0020-9996     ISO Abbreviation:  Invest Radiol     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1992-07-23     Completed Date:  1992-07-23     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0045377     Medline TA:  Invest Radiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  436-42     Citation Subset:  IM    
Department of Analytical Radiology, Osaka University Medical School, Japan.
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MeSH Terms
Contrast Media*
Coronary Disease / radiography*
Heart / radiography*
Middle Aged
Tomography, X-Ray Computed / methods*
Reg. No./Substance:
0/Contrast Media

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