Document Detail

Quantitative assessment of microcollateral recruitment during coronary occlusion using real-time intravenous myocardial contrast echocardiography.
MedLine Citation:
PMID:  17628411     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Residual collateral-derived myocardial blood flow (MBF) (A x beta) is important to protect against myocardial ischemia after acute coronary occlusion. METHODS: Recruitment of microcollateral was assessed in 22 dogs with left circumflex coronary artery occlusion by analysis of MBF and regional wall thickening (WT) using real-time myocardial contrast echocardiography. RESULTS: Video intensity and WT at the center of risk area were significantly lower than those at the border of risk area. The video intensity, A value, beta value, and MBF correlated well with WT after left circumflex coronary artery occlusion. The WT of the area with above 25% of normal MBF was preserved and was higher than that at below 25%. However, the deterioration of WT was not distinguished according to A value. CONCLUSION: Real-time myocardial contrast echocardiography is a useful noninvasive method to evaluate collateral-derived MBF, which can be a reliable index of protection against myocardial ischemia.
Fuminobu Ishikura; Kentaro Otani; Hiroyuki Kayano; Tsutomu Toshida; Akiko Iwata; Toshihiko Asanuma; Masafumi Kitakaze; Yoshihiro Shinozaki; Hidezo Mori; Shintaro Beppu
Publication Detail:
Type:  Journal Article     Date:  2007-07-12
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  21     ISSN:  1097-6795     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-11     Completed Date:  2008-03-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  139-45     Citation Subset:  IM    
School of Allied Health Sciences, Osaka University, Faculty of Medicine, Osaka, Japan.
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MeSH Terms
Collateral Circulation*
Contrast Media
Coronary Circulation*
Coronary Stenosis / physiopathology,  ultrasonography*
Disease Models, Animal
Echocardiography, Doppler*
Fractional Flow Reserve, Myocardial
Hemodynamics / physiology
Infusions, Intravenous
Linear Models
Myocardial Infarction / prevention & control,  ultrasonography
Sensitivity and Specificity
Reg. No./Substance:
0/Contrast Media

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