Document Detail

Quantitative assessment of aqueous flare: the effect of age and pupillary dilation.
MedLine Citation:
PMID:  12358291     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the effect of age and pupillary dilation on aqueous flare. METHODS: In this study, 100 eyes of 100 patients ranging in ages from 23 to 84 years were examined. Anterior chamber flare was measured before and after pupillary dilation using the Kowa laser flare meter (FM-500). Predilation and postdilation flare counts were compared by paired t-test. Stepwise regression analysis was then used to determine the effect of demographic variables on pre- and postdilation flare as well as the difference between pre-and postdilation flare counts. RESULTS: The predilation and postdilation flare counts correlated with age (P < 0.0001 for both pre-and postdilation flare counts). Correlation coefficient between age and flare measurements was R2 = 0.58 predilation and 0.63 postdilation. Flare intensity significantly decreased after pupillary dilation (P < 0.001). CONCLUSIONS: Anterior chamber flare increases with age. It might be related to blood-aqueous barrier instability. Pupillary dilation significantly decreases flare counts suggesting that aqueous protein concentration is dependent on aqueous flow rates.
Sherif M El-Harazi; Richard S Ruiz; Robert M Feldman; Alice Z Chuang; Guillermina Villanueva
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Ophthalmic surgery and lasers     Volume:  33     ISSN:  1082-3069     ISO Abbreviation:  Ophthalmic Surg Lasers     Publication Date:    2002 Sep-Oct
Date Detail:
Created Date:  2002-10-02     Completed Date:  2003-01-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9517132     Medline TA:  Ophthalmic Surg Lasers     Country:  United States    
Other Details:
Languages:  eng     Pagination:  379-82     Citation Subset:  IM    
Department of Ophthalmology and Visual Science, The University of Texas Health Science Center, Houston, USA.
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MeSH Terms
Age Factors
Aged, 80 and over
Anterior Chamber / pathology*
Aqueous Humor / cytology*
Blood-Aqueous Barrier
Cell Count
Lasers / diagnostic use
Middle Aged
Mydriatics / administration & dosage
Prospective Studies
Pupil / drug effects*
Tropicamide / administration & dosage
Uveitis, Anterior / diagnosis*
Reg. No./Substance:
0/Mydriatics; 1508-75-4/Tropicamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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