Document Detail

Quantitative analysis of semi-supine exercise echocardiography--influence of age on myocardial Doppler imaging indices.
MedLine Citation:
PMID:  16869446     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: This study was performed to evaluate the feasibility of quantitative analysis of exercise echocardiography using pulsed wave Doppler myocardial imaging (DMI) and to examine the relation between age and DMI parameters at rest and during graded exercise in normal subjects. METHODS AND RESULTS: Seventy-two healthy volunteers were divided into three age groups (group I, age < or = 40 years, group II, age 41 - 59 years and group III, age > or = 60 years), and underwent a semi-supine exercise echocardiogram. Peak systolic velocity (SV), time to peak SV (TPV), systolic velocity time integral (VTI) and peak diastolic velocities (VE and VA) were measured off-line. There was a heterogeneity in DMI parameters between different myocardial walls and a gradient was found between basal and mid segments. Both persisted during exercise. Group I had significantly higher TPV than groups II and III. Increase in workload was accompanied by an increase in velocities, while TPV decreased. Differences between groups persisted throughout exercise. CONCLUSIONS: Off-line measurements of DMI parameters are feasible during exercise. SV and E decline as age increases while A increases. SV already increases at low charge exercise and may serve as a quantitative marker for the detection of myocardial viability. Change of the absolute DMI velocity values during exercise may provide a better indicator of ischaemia or viability than the absolute values themselves.
Evdokia Petropoulou; Patrizio Lancellotti; Luc A Piérard
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta cardiologica     Volume:  61     ISSN:  0001-5385     ISO Abbreviation:  Acta Cardiol     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-07-27     Completed Date:  2007-01-12     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  0370570     Medline TA:  Acta Cardiol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  271-7     Citation Subset:  IM    
Department of Cardiology, University Hospital of Liège, Belgium.
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MeSH Terms
Age Factors
Blood Pressure / physiology
Diastole / physiology
Echocardiography / methods*
Echocardiography, Doppler*
Echocardiography, Stress / methods*
Feasibility Studies
Heart Rate / physiology
Image Processing, Computer-Assisted*
Middle Aged
Myocardial Contraction / physiology
Physical Exertion / physiology
Reference Values
Statistics as Topic
Stroke Volume / physiology
Supine Position / physiology*
Systole / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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