Document Detail

Quantitative analysis of placental vasculature by three-dimensional power Doppler ultrasonography in normal pregnancies from 12 to 40 weeks of gestation.
MedLine Citation:
PMID:  19073343     Owner:  NLM     Status:  MEDLINE    
Evaluate the distribution and variation of placental vascular indices according to gestational age and placental volume. From March to November 2007, three-dimensional (3D)-power Doppler ultrasound was performed in 295 normal pregnancies from 12 to 40 weeks of gestation. Using the same preestablished settings for all patients, power Doppler was applied to the placenta and placental volume was obtained by the rotational technique (VOCAL). The 3D-power histogram was used to determine the placental vascular indices: vascularization index (VI), flow index (FI) and vascularization-flow index (VFI). The placental vascular indices were then plotted against gestational age and placental volume. All placental vascular indices showed constant distribution throughout gestation. A tendency for a reduction in placental vascular indices with increased placental volume was observed, but was only statistically significant when placental FI was considered (p<0.05). All placental vascular indices estimated by 3D-power Doppler ultrasonography presented constant distribution throughout gestation, despite the increase in placental volume according to gestational age.
C F S de Paula; R Ruano; J A D B Campos; M Zugaib
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Publication Detail:
Type:  Journal Article     Date:  2008-12-13
Journal Detail:
Title:  Placenta     Volume:  30     ISSN:  0143-4004     ISO Abbreviation:  Placenta     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-01-23     Completed Date:  2009-03-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8006349     Medline TA:  Placenta     Country:  England    
Other Details:
Languages:  eng     Pagination:  142-8     Citation Subset:  IM    
Obstetrics Department, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
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MeSH Terms
Blood Flow Velocity
Gestational Age*
Imaging, Three-Dimensional
Placenta / anatomy & histology,  blood supply*,  ultrasonography*
Placental Circulation / physiology*
Ultrasonography, Doppler / methods*
Ultrasonography, Prenatal*
Young Adult

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