| Quantitative analysis of hypertrophy in cardiac chambers in cyanotic tetralogy of Fallot. | |
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MedLine Citation:
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PMID: 11384078 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although early total corrective repair for cyanotic tetralogy of Fallot is now safely performed at many institutions, long-term complications after surgical repair have been demonstrated. Therefore, the optimal procedure and timing for surgical treatment remain controxersial. In the present study, we conducted a quantitative analysis of the hypertrophy of all four chambers of 87 autopsied hearts of cyanotic tetralogy of Fallot and 71 normal control hearts utilizing the myocardial mass index, and evaluated the progression of lesions with advancing age. In cyanotic tetralogy of Fallot, hypertrophy of the right ventricle progresses immediately after birth, with that of the right atrium developing soon after. The left side of the heart is normal or slightly atrophied which could be corrected by sufficient palliative intervention or total corrective repair. The growth curves of both ventricles were parallel to those of normal hearts for the period studied. Pulmonary atresia, palliative operation, and total corrective repair have been shown to have some influence on the morphological characteristics of hearts of cyanotic tetralogy of Fallot. |
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Authors:
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M Noma; A Sekiguchi; M Chikada; A Ishizawa; J Miyauchi; R Okada |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Japanese heart journal Volume: 42 ISSN: 0021-4868 ISO Abbreviation: Jpn Heart J Publication Date: 2001 Mar |
Date Detail:
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Created Date: 2001-05-31 Completed Date: 2001-06-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401175 Medline TA: Jpn Heart J Country: Japan |
Other Details:
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Languages: eng Pagination: 173-84 Citation Subset: IM |
Affiliation:
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Division of Cardiovascular Surgery, National Children's Hospital, Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Child, Preschool Heart Atria / pathology Humans Hypertrophy, Left Ventricular / pathology Hypertrophy, Right Ventricular / pathology Infant Myocardium / pathology* Tetralogy of Fallot / pathology*, surgery |
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