Document Detail

Quantitative analysis of ataxic gait in patients with schizophrenia: the influence of age and visual control.
MedLine Citation:
PMID:  17512059     Owner:  NLM     Status:  MEDLINE    
Previous research has determined that patients with schizophrenia classically exhibit ataxic gait. Age and visual controls of balance are important factors, and may influence gait, but have not been controlled. A total of 100 patients with schizophrenia were included in this study, along with 50 age- and sex-matched healthy controls. They were sampled with methods which stratified both groups according to age and sex. Tandem gait tests were conducted with eyes open and closed, and gait parameters were assessed by the footprint method. Ataxic gait was found to be significantly more frequent in the schizophrenic group. With eyes open, ataxic gait showed a significant increase with age in the schizophrenic group, but not in the healthy control group. Adjusting ataxic gait of the patients on the basis of the normal age effects measured in the healthy control group, the ataxic gait in the schizophrenic group increased according to age. Multiple logistic regression analysis revealed that old age and previous history of alcohol dependence/abuse were the risk factors for ataxic gait with eyes open. This implies that a dysfunction of the visuo-cerebellar circuit in patients with schizophrenia increases according to age.
Hong Jin Jeon; Maeng Je Cho; Seong-Jin Cho; Seon-Uk Kim; Soo-Kyung Park; Jun Soo Kwon; Jae Yong Jeon; Bong-Jin Hahm
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-05-23
Journal Detail:
Title:  Psychiatry research     Volume:  152     ISSN:  0165-1781     ISO Abbreviation:  Psychiatry Res     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-13     Completed Date:  2007-12-07     Revised Date:  2008-04-17    
Medline Journal Info:
Nlm Unique ID:  7911385     Medline TA:  Psychiatry Res     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  155-64     Citation Subset:  IM    
Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea.
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MeSH Terms
Age Factors
Antipsychotic Agents / therapeutic use
Ataxia / epidemiology*,  physiopathology*
Cerebellum / physiopathology
Drug Administration Schedule
Middle Aged
Schizophrenia / diagnosis,  epidemiology*
Vision Disorders / diagnosis,  epidemiology*
Reg. No./Substance:
0/Antipsychotic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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