Document Detail


Quantitative analysis of ataxic gait in patients with schizophrenia: the influence of age and visual control.
MedLine Citation:
PMID:  17512059     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Previous research has determined that patients with schizophrenia classically exhibit ataxic gait. Age and visual controls of balance are important factors, and may influence gait, but have not been controlled. A total of 100 patients with schizophrenia were included in this study, along with 50 age- and sex-matched healthy controls. They were sampled with methods which stratified both groups according to age and sex. Tandem gait tests were conducted with eyes open and closed, and gait parameters were assessed by the footprint method. Ataxic gait was found to be significantly more frequent in the schizophrenic group. With eyes open, ataxic gait showed a significant increase with age in the schizophrenic group, but not in the healthy control group. Adjusting ataxic gait of the patients on the basis of the normal age effects measured in the healthy control group, the ataxic gait in the schizophrenic group increased according to age. Multiple logistic regression analysis revealed that old age and previous history of alcohol dependence/abuse were the risk factors for ataxic gait with eyes open. This implies that a dysfunction of the visuo-cerebellar circuit in patients with schizophrenia increases according to age.
Authors:
Hong Jin Jeon; Maeng Je Cho; Seong-Jin Cho; Seon-Uk Kim; Soo-Kyung Park; Jun Soo Kwon; Jae Yong Jeon; Bong-Jin Hahm
Related Documents :
11415629 - Relationship between vertical ground reaction force and speed during walking, slow jogg...
8311679 - Postural sway patterns of normal men and women and men with mental retardation during a...
18042999 - Gait speed predicts decline in attention and psychomotor speed in older adults: the hea...
9549709 - Functional ability perceived by individuals following total knee arthroplasty compared ...
21651999 - Cell type-specific responses of peripheral blood mononuclear cells to silver nanopartic...
9674519 - Balance disorders in older persons: quantification with posturography.
6746939 - Recovery from severe closed head injuries: repeat testings with the halstead-reitan neu...
20575789 - Catalase as a regulator of the propensity to ingest alcohol in genetically determined a...
12924649 - Risk factors for dysplasia in patients with barrett's esophagus (be): results from a mu...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-05-23
Journal Detail:
Title:  Psychiatry research     Volume:  152     ISSN:  0165-1781     ISO Abbreviation:  Psychiatry Res     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-13     Completed Date:  2007-12-07     Revised Date:  2008-04-17    
Medline Journal Info:
Nlm Unique ID:  7911385     Medline TA:  Psychiatry Res     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  155-64     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Antipsychotic Agents / therapeutic use
Ataxia / epidemiology*,  physiopathology*
Cerebellum / physiopathology
Drug Administration Schedule
Female
Gait*
Humans
Male
Middle Aged
Schizophrenia / diagnosis,  epidemiology*
Vision Disorders / diagnosis,  epidemiology*
Chemical
Reg. No./Substance:
0/Antipsychotic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Depression profile in patients with and without chronic heart failure.
Next Document:  Transportation stress in young bulls alters expression of neutrophil genes important for the regulat...