Document Detail

Quantitative analysis of amniotic fluid phospholipids in diabetic pregnant women.
MedLine Citation:
PMID:  3737062     Owner:  NLM     Status:  MEDLINE    
Controversy exists regarding the fetal lung maturity profiles in diabetic and normal pregnancies. Diabetic and control patients at term were compared. A comprehensive lung profile was obtained using high performance liquid chromatography, lecithin:sphingomyelin ratio by conventional thin-layer chromatography, and the Lumadex foam stability index. There was no statistically significant difference in the phospholipids measured by any of the three techniques despite the fact that the control patients had a significantly higher mean gestational age at amniocentesis. As expected, the diabetic pregnancies had a significantly higher mean birth weight. There was no case of respiratory distress syndrome in either group. The present data do not allow rejection of the null hypothesis of no difference in amniotic fluid phospholipids, between diabetic and normal pregnancy, at term.
E Amon; J Lipshitz; B M Sibai; T N Abdella; D W Whybrew; A el-Nazer
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  68     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1986 Sep 
Date Detail:
Created Date:  1986-09-17     Completed Date:  1986-09-17     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  373-8     Citation Subset:  AIM; IM    
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MeSH Terms
Amniotic Fluid / analysis*
Birth Weight
Cesarean Section
Chromatography, High Pressure Liquid
Fetal Organ Maturity
Gestational Age
Lung / embryology*
Phosphatidylcholines / analysis*
Phosphatidylglycerols / analysis
Pregnancy in Diabetics*
Sphingomyelins / analysis*
Reg. No./Substance:
0/Phosphatidylcholines; 0/Phosphatidylglycerols; 0/Sphingomyelins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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