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Quantitative acid-base physiology using the Stewart model. Does it improve our understanding of what is really wrong?
MedLine Citation:
PMID:  16864007     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Traditional theories of acid-base balance are based on the Henderson-Hasselbalch equation to calculate proton concentration. The recent revival of quantitative acid-base physiology using the Stewart model has increased our understanding of complicated acid-base disorders, but has also led to several new controversies. With the help of three patient histories, we show that the Henderson-Hasselbalch equation should be regarded as a simplified version of the more general Stewart model and not as something completely different. Therefore, both models may be useful at the bedside.
Authors:
R Derksen; G J Scheffer; J G van der Hoeven
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of internal medicine     Volume:  17     ISSN:  0953-6205     ISO Abbreviation:  Eur. J. Intern. Med.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9003220     Medline TA:  Eur J Intern Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  330-3     Citation Subset:  -    
Affiliation:
Department of Anesthesiology, University Medical Centre Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
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