Document Detail

Quantitative dermal measurements following treatment with AirGent.
MedLine Citation:
PMID:  20884902     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: As an alternative to other minimally-invasive approaches to facial rejuvenation, enhancement and treatment of the dermis with a compressed air molecule of hyaluronic acid (HA) is a promising method in that it lacks some of the drawbacks of other procedures. The novelty of these systems, one of which is tested in this study, is based on the supposition that jet lateral dispersion of HA produces both instant dermal augmentation and specific wound-healing processes, leading to its long-term dermal thickening.
OBJECTIVES: The authors report on the efficacy and safety of the AirGent system (PerfAction, Rehovot, Israel), which is a renewal system designed to initiate a wound-healing process in the dermal layer. It is a computer-guided system that delivers treatment through compressed air molecules of HA to the dermal layer of the skin.
METHODS: The authors treated 20 patients (a total of 105 treatment sessions) with the AirGent system between May 2008 and November 2008. Each patient received three treatments at three- to four-week intervals. Each patient's skin thickness was measured with ultrasonography pretreatment, immediately after each session, and at six months posttreatment.
RESULTS: Seven days after the last procedure, an increase in skin thickness was observed in all patients. The most significant differences were noted in the upper lip area, where the thickness had increased by an average of 1.3 mm. Six months after the last session, an increase in skin thickness was still noted in most patients, at which time the biggest difference was noted around the eyes, where the skin remained thicker by an average of 0.77 mm over baseline. According to the results of the Global Improvement Assessment questionnaire, at the six-month follow-up to evaluate their satisfaction with the long-term results, at least 59.9% of patients still noted at least a slight improvement in their appearance.
CONCLUSIONS: Although a small group of patients and a relatively short period of observation limit the scope of our conclusions, the data show that the AirGent system is efficacious in producing increases in skin thickness that correlate with at least a substantial or slight improvement of appearance, as reported by the patients themselves.
Kazimierz F Kobus; Tomasz Dydymski
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery     Volume:  30     ISSN:  1527-330X     ISO Abbreviation:  Aesthet Surg J     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-10-01     Completed Date:  2011-01-13     Revised Date:  2011-09-12    
Medline Journal Info:
Nlm Unique ID:  9707469     Medline TA:  Aesthet Surg J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  725-9     Citation Subset:  IM    
Department of Plastic Surgery, Specialist Medical Center, Polanica Zdroj, Poland.
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MeSH Terms
Cosmetic Techniques
Follow-Up Studies
Hyaluronic Acid / administration & dosage*
Middle Aged
Patient Satisfaction
Skin / metabolism
Skin Aging / drug effects*
Therapy, Computer-Assisted / methods
Treatment Outcome
Ultrasonography / methods
Wound Healing / drug effects*
Reg. No./Substance:
9004-61-9/Hyaluronic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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