Document Detail


Quantitative comparison of ginsenosides and polyacetylenes in wild and cultivated American ginseng.
MedLine Citation:
PMID:  20397232     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Quantitative comparison of seven ginsenosides in wild and cultivated American ginseng revealed that the Rg(1)/Rd ratio presented a significantly large difference between cultivated and type-I (one of the defined chemotypes) wild American ginseng, facilitating this ratio as a characteristic marker for differentiating these two groups. Similarly, the ratio (Rg(1)+Re)/Rd, and the ratio of protopanaxatriol (PPT)-type ginsenosides to protopanaxadiol (PPD)-type ginsenosides showed a large difference between these two groups. On the other hand, type-II wild samples were found to have high Rg(1)/Rb(1) and Rg(1)/Re ratios and low panaxydol/panaxynol ratio, which is entirely different from Type-I American ginseng, but is very similar to that of Asian ginseng. This not only suggests that the chemotype should be taken into consideration properly when using these parameters for differentiating American and Asian ginseng, but also indicates that type-II wild American ginseng may have distinct pharmacological activities and therapeutic effects.
Authors:
Jing-Rong Wang; Chiu-Yin Leung; Hing-Man Ho; Stella Chai; Lee-Fong Yau; Zhong-Zhen Zhao; Zhi-Hong Jiang
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chemistry & biodiversity     Volume:  7     ISSN:  1612-1880     ISO Abbreviation:  Chem. Biodivers.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-21     Completed Date:  2010-07-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101197449     Medline TA:  Chem Biodivers     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  975-83     Citation Subset:  IM    
Affiliation:
School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong.
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MeSH Terms
Descriptor/Qualifier:
Chromatography, High Pressure Liquid
Ginsenosides / analysis*,  chemistry,  isolation & purification
Panax / chemistry*
Plant Roots / chemistry
Polyacetylenes / analysis*,  chemistry,  isolation & purification
Chemical
Reg. No./Substance:
0/Ginsenosides; 25067-58-7/Polyacetylenes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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