Document Detail

Quantitative analysis of stress echocardiograms in healthy horses with 2-dimensional (2D) echocardiography, anatomical M-mode, tissue Doppler imaging, and 2D speckle tracking.
MedLine Citation:
PMID:  20561187     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Stress echocardiography is used to diagnose myocardial dysfunction in horses, but current methods are not well standardized. The influence of heart rate (HR) on measurements is largely unknown. OBJECTIVES: To investigate the use of 2-dimensional echocardiography (2DE), anatomical M-mode (AMM), tissue Doppler imaging (TDI), and 2D speckle tracking (2DST) at rest and after exercise for quantification of regional and global left-ventricular (LV) function. ANIMALS: Five athletic Warmblood horses; 11.6+/-3.6 years; 529+/-48 kg. METHODS: Prospective study. Three separate echocardiographic examinations were performed before (baseline) and over 5 minutes after treadmill exercise with 2DE (1st, short-axis view; 2nd, long-axis view) and pulsed-wave TDI (3rd examination). Offline analyses were performed at baseline and after exercise at HR 120, 110, 100, 90, and 80 minute(-1). Global and segmental measurements were compared by analysis of variance. RESULTS: Quantitative analyses of stress echocardiograms were feasible in all horses. None of the AMM indices changed significantly after exercise. Stroke volume and ejection fraction by 2DE and strain by 2DST decreased, whereas strain rate by 2DST increased significantly at HR>100 minute(-1). TDI analyses were technically difficult and provided little additional information. CONCLUSIONS AND CLINICAL IMPORTANCE: Volumetric indices by 2DE and strain and strain rate by 2DST are applicable for quantitative assessment of stress echocardiograms. In healthy horses, they are significantly altered at a HR>100 minute(-1) and need to be evaluated in view of the instantaneous HR. Further investigations are needed to define the clinical value of stress echocardiography in horses with cardiac disease.
K D Schefer; C Bitschnau; M A Weishaupt; C C Schwarzwald
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Publication Detail:
Type:  Journal Article     Date:  2010-06-18
Journal Detail:
Title:  Journal of veterinary internal medicine / American College of Veterinary Internal Medicine     Volume:  24     ISSN:  0891-6640     ISO Abbreviation:  J. Vet. Intern. Med.     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-07-23     Completed Date:  2010-09-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708660     Medline TA:  J Vet Intern Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  918-31     Citation Subset:  IM    
Equine Department, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
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MeSH Terms
Echocardiography, Stress / methods,  veterinary*
Exercise Test / veterinary*
Heart Ventricles / anatomy & histology
Horses / physiology*
Ventricular Function / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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