| Quantitative 35Cl nuclear quadrupole resonance in tablets of the antidiabetic medicine Diabinese. | |
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MedLine Citation:
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PMID: 19492808 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pulsed (35)Cl nuclear quadrupole resonance (NQR) experiments have been performed on 250-mg tablets of the antidiabetic medicine Diabinese to establish the conditions needed for noninvasive quantitative analysis of the medicine in standard bottles. One important condition is the generation of a uniform radio-frequency (RF) field over the sample, which has been achieved by two designs of sample coil: one of variable pitch, and the other a resonator that has been fabricated from a single turn of copper sheet with a longitudinal gap bridged by tuning capacitors. The results from blind tests show that the number of tablets in a bottle could be predicted to within +/-3%. |
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Authors:
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Elizabeth Tate; Kaspar Althoefer; Jamie Barras; Michael D Rowe; John A S Smith; Gareth E S Pearce; Stephen A C Wren |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Analytical chemistry Volume: 81 ISSN: 1520-6882 ISO Abbreviation: Anal. Chem. Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-06-30 Completed Date: 2009-09-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370536 Medline TA: Anal Chem Country: United States |
Other Details:
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Languages: eng Pagination: 5574-6 Citation Subset: IM |
Affiliation:
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King's College London, Department of Mechanical Engineering, Strand, London, WC2R 2LS, United Kingdom. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chlorine
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chemistry Chlorpropamide / chemistry* Hypoglycemic Agents / chemistry* Isotope Labeling Magnetic Resonance Spectroscopy / methods* Radio Waves Tablets |
| Chemical | |
Reg. No./Substance:
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0/Hypoglycemic Agents; 0/Tablets; 7782-50-5/Chlorine; 94-20-2/Chlorpropamide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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