Document Detail

Quantification of regional pulmonary flow with 9mTc-MAA SPECT and cine phase contrast MR imaging.
MedLine Citation:
PMID:  12416583     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to evaluate the relationship between left and right pulmonary arterial flow measured by cine phase contrast magnetic resonance imaging (cine PCMRI) and the distribution of perfusion on 99mTc-MAA SPECT and to determine whether the regional pulmonary flow quantification was feasible with the combined use of these techniques. Twenty patients with different pulmonary diseases were evaluated. Left and right lung counts on 99mTc-MAA SPECT images were separately summed and the left-to-total count ratio was calculated. The left-to-total pulmonary flow ratio was calculated from the left and right main pulmonary flows measured with cine PCMRI. We evaluated the correlation and agreement between the ratio determined with 99mTc-MAA SPECT and cine PCMRI by linear regression analysis and Bland-Altman analysis. The left-to-total ratios obtained by 99mTc-MAA and cine PCMRI were 52.0 +/- 22.1% and 52.2 +/- 20.8%, respectively, and showed a strong correlation (r = 0.99, p < 0.001). The mean difference between the two methods in the ratio was 0.25 +/- 2.3% with a 95% confidence interval from -0.84 to 1.34. The results showed that the regional pulmonary flow was calculated with both the left and right pulmonary flow measured with cine PCMRI and the ratio of regional distribution on 99Tc-MAA SPECT images.
Hisato Osada; Kikuo Machida; Norinari Honda
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of nuclear medicine     Volume:  16     ISSN:  0914-7187     ISO Abbreviation:  Ann Nucl Med     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-11-05     Completed Date:  2003-04-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8913398     Medline TA:  Ann Nucl Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  423-9     Citation Subset:  IM    
Department of Radiology, Saitama Medical Center, Saitama Medical School, Kawagoe, Japan.
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MeSH Terms
Aged, 80 and over
Feasibility Studies
Lung / blood supply,  radionuclide imaging*
Lung Diseases / diagnosis*
Magnetic Resonance Imaging, Cine / methods*
Middle Aged
Pulmonary Artery / anatomy & histology*
Pulmonary Circulation*
Radiopharmaceuticals / diagnostic use
Reproducibility of Results
Sensitivity and Specificity
Statistics as Topic
Technetium Tc 99m Aggregated Albumin / diagnostic use*
Tomography, Emission-Computed, Single-Photon / methods*
Reg. No./Substance:
0/Radiopharmaceuticals; 0/Technetium Tc 99m Aggregated Albumin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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