Document Detail


Quantification of regional myocardial perfusion using semiautomated translation-free analysis of contrast-enhanced power modulation images.
MedLine Citation:
PMID:  12574737     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Quantitative analysis of myocardial perfusion is currently based on manual tracing and frame-by-frame realignment of regions of interest. We developed a technique for semiautomated identification of myocardial regions from power modulation images as a potential tool for quantification of myocardial contrast enhancement. This approach was tested in 13 anesthetized pigs during continuous intravenous infusion of contrast at baseline, left anterior descending coronary artery occlusion, and reperfusion. Regional pixel intensity was calculated for each consecutive end-systolic frame after a high-energy ultrasound impulse, and fitted with an exponential function. Perfusion defects caused by occlusion of left anterior descending coronary artery were confirmed by a significant decrease in both postimpulse steady-state intensity and the initial rate of contrast replenishment (P <.05), which were reversed with reperfusion. Automated measurements of myocardial intensity correlated highly with conventional manual tracing (r = 0.90 to 0.97), and resulted in improved signal-to-noise ratios. This technique allows translation-free quantification of regional myocardial perfusion, without the need for manual tracing.
Authors:
Enrico G Caiani; Roberto M Lang; Serena Caslini; Keith A Collins; Claudia E Korcarz; Victor Mor-Avi
Related Documents :
4053297 - Effect of cardiotropic agents on the myocardial dysfunction of hyperdynamic sepsis.
16980717 - Primary myocardial involvement in systemic sclerosis.
10649197 - Is there a relationship between systemic perfusion temperature during coronary artery b...
22841017 - Perioperative serum aspartate aminotransferase level as a predictor of survival after c...
24498007 - Galectin-1 in early acute myocardial infarction.
20174637 - Improved energy supply regulation in chronic hypoxic mouse counteracts hypoxia-induced ...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  16     ISSN:  0894-7317     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-02-07     Completed Date:  2003-05-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  116-23     Citation Subset:  IM    
Affiliation:
Noninvasive Cardiac Imaging Laboratory, University of Chicago, USA. caiani@biomed.polimi.it
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Algorithms
Animals
Feasibility Studies
Image Enhancement*
Image Processing, Computer-Assisted / methods*
Myocardium / metabolism*
Swine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Rapid freehand scanning three-dimensional echocardiography: accurate measurement of left ventricular...
Next Document:  Contrast-enhanced Doppler hemodynamics for noninvasive assessment of patients with chronic heart fai...