Document Detail

Quantification of pulmonary and systemic blood flow by magnetic resonance velocity mapping in the assessment of atrial-level shunts.
MedLine Citation:
PMID:  8915715     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to asses the feasibility and accuracy of magnetic resonance (MR) velocity mapping to calculate pulmonary-to-systemic flow ratio (Qp:Qs) in patients with a suspected or diagnosed atrial-level shunt. During a one-year period, all patients referred to our department for further evaluation of an atrial-level shunt underwent the same imaging protocol. Multiphase-multisection gradient-echo MR image sets of the heart were acquired to measure left and right ventricular stroke volumes for validation. Ascending aorta and main pulmonary artery volume flow were measured with MR velocity mapping. Qp:Qs ratios were calculated from both stroke volume data and flow data. Twelve patients, including 6 children, were studied. Six patients had an established diagnosis of atrial septal defect, and the other 6 patients were suspected to have an atrial-level shunt. Measurements of left and right ventricular stroke corresponded closely with those of aortic (r = 0.98) and pulmonary flow (r = 0.99) respectively, and Qp:Qs flow ratios agreed with stroke volume ratios (r = 0.92). In 5 patients with a suspected shunt, the diagnosis could be rejected. Shunts were demonstrated in the other 7 patients. M(r) velocity mapping offers an accurate method to measure aortic and pulmonary artery volume flow that can be useful in the evaluation of atrial-level shunts, in order to establish a definite diagnosis and/or to quantify the Qp:Qs ratio.
S A Rebergen; E E van der Wall; W A Helbing; A de Roos; A E van Voorthuisen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of cardiac imaging     Volume:  12     ISSN:  0167-9899     ISO Abbreviation:  Int J Card Imaging     Publication Date:  1996 Sep 
Date Detail:
Created Date:  1997-02-25     Completed Date:  1997-02-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8600426     Medline TA:  Int J Card Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  143-52     Citation Subset:  IM    
Department Diagnostic Radiology and Nuclear Medicine, Leiden University Hospital, The Netherlands.
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MeSH Terms
Blood Circulation / physiology*
Blood Flow Velocity
Feasibility Studies
Heart Septal Defects, Atrial / physiopathology*
Image Processing, Computer-Assisted
Magnetic Resonance Angiography* / methods
Pulmonary Circulation / physiology*
Comment In:
Int J Card Imaging. 1996 Sep;12(3):213-4   [PMID:  8915723 ]
Int J Card Imaging. 1996 Sep;12(3):215-7   [PMID:  8915724 ]

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