Document Detail

Quantification of phosphatidic acid in foodstuffs using TLC-imaging technique.
MedLine Citation:
PMID:  22475031     Owner:  NLM     Status:  Publisher    
Apical application of lysophosphatidic acid (LPA), a growth factor-like phospholipid, was shown to prevent or restore gastrointestinal (GI) disorders, such as diarrhea and stomach ulcer in experimental animals. Since LPA is formed from phosphatidic acid (PA) by the activity of digestive phospholipase A2, PA is a potential component for dietary treatment of such GI disorders. Here, we quantified PA contained in 38 foodstuffs and 3 herbs by TLC-imaging technique. Vegetables belonging to Brassicaceae, such as cabbage leaves (700 nmol/g wet weight) and Japanese radish leaves (570 nmol/g), contained higher amounts of PA than other foodstuffs. Amounts of PA in fruits, cereals and starchy root vegetables were below 300 nmol/g. Animal foodstuffs contained low amounts of PA (<60 nmol/g). Interestingly, leaves of Mallotus japonicas, a Japanese edible herb used for treatment of stomach ulcer, had the highest PA (1410 nmol/g) among those examined. The data shown here will be useful for the development of dietary treatment for damaged GI tract.
Tamotsu Tanaka; Ayaka Kassai; Mayumi Ohmoto; Katsuya Morito; Yoshiki Kashiwada; Yoshihisa Takaishi; Mai Urikura; Jun-Ichi Morishige; Kiyoshi Satouchi; Akira Tokumura
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-4
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  -     ISSN:  1520-5118     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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