| Quantification of myocardial blood flow: what is the clinical role? | |
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MedLine Citation:
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PMID: 19306770 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Quantification of regional myocardial blood flow and of its responses to targeted physiologic and pharmacologic interventions, which is now available with positron emitting tracers of blood flow and positron emission tomography (PET), extends the diagnostic potential of standard myocardial perfusion imaging. These noninvasive flow measurements serve as tools for quantifying functional consequences of epicardial coronary artery disease, as well as of impairments in microcirculatory reactivity that escape detection by standard perfusion imaging. Flow measurements are clinically useful for more comprehensively assessing the extent and severity of coronary vascular disease or impairments in microcirculatory function in noncoronary cardiac disease. Flow estimates in these disorders contain independent or unique prognostic information about future major cardiac events. Flow measurements are also useful for assessing the coronary risk, for predicting long-term cardiovascular events, and for monitoring the effectiveness of risk reduction strategies. |
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Authors:
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Heinrich R Schelbert |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Cardiology clinics Volume: 27 ISSN: 1558-2264 ISO Abbreviation: Cardiol Clin Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-03-24 Completed Date: 2009-06-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8300331 Medline TA: Cardiol Clin Country: Netherlands |
Other Details:
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Languages: eng Pagination: 277-89, Table of Contents Citation Subset: IM |
Affiliation:
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Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, CA 90095-6948, USA. hschelbert@mednet.ucla.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Coronary Circulation
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physiology* Coronary Disease / physiopathology*, radionuclide imaging Coronary Vessels / physiopathology, radionuclide imaging* Humans Positron-Emission Tomography / methods* Regional Blood Flow / physiology Reproducibility of Results |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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