Document Detail


Quantification of left ventricular volumes and ejection fraction from gated 99mTc-MIBI SPECT: validation of an elastic surface model approach in comparison to cardiac magnetic resonance imaging, 4D-MSPECT and QGS.
MedLine Citation:
PMID:  17216166     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The segmentation algorithm ESM based on an elastic surface model was validated for the assessment of left ventricular volumes and ejection fraction from ECG-gated myocardial perfusion SPECT. Additionally, it was compared with the commercially available quantification packages 4D-MSPECT and QGS. Cardiac MRI was used as the reference method. METHODS: SPECT and MRI were performed on 70 consecutive patients with suspected or proven coronary artery disease. End-diastolic (EDV) and end-systolic (ESV) volumes and left ventricular ejection fraction (LVEF) were derived from SPECT studies by using the segmentation algorithms ESM, 4D-MSPECT and QGS and from cardiac MRI. RESULTS: ESM-derived values for EDV and ESV correlated well with those from cardiac MRI (correlation coefficients R=0.90 and R=0.95, respectively), as did the measurements for LVEF (R=0.86). Both EDV and ESV were slightly overestimated for larger ventricles but not for smaller ventricles; LVEF was slightly overestimated irrespective of ventricle size. The above correlation coefficients are comparable to those for the 4D-MSPECT and QGS segmentation algorithms. However, results obtained with the three segmentation algorithms are not interchangeable. CONCLUSION: The ESM algorithm can be used to assess EDV, ESV and LVEF from gated perfusion SPECT images. Overall, the performance was similar to that of 4D-MSPECT and QGS when compared with cardiac MRI. Results obtained with the three tested segmentation methods are not interchangeable, so that the same algorithm should be used for follow-up studies and control subjects.
Authors:
Lars Stegger; Claudia S A Lipke; Peter Kies; Bernd Nowak; Otmar Schober; Udalrich Buell; Michael Schäfers; Wolfgang M Schaefer
Related Documents :
8781836 - Morphological bases for thallium-201 uptake in cardiac imaging and correlates with myoc...
10901456 - Effect of temporal sampling on evaluation of left ventricular ejection fraction by mean...
18513646 - Individual differences in the effectiveness of intracoronary bone marrow cell transplan...
15096996 - Myocardial viability evaluation using magnetocardiography in patients with coronary art...
11440496 - Cardiac surgery in octogenarians; peri-operative outcome and long-term results.
12899396 - Dobutamine magnetic resonance imaging predicts contractile reserve of chronically dysfu...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-01-10
Journal Detail:
Title:  European journal of nuclear medicine and molecular imaging     Volume:  34     ISSN:  1619-7070     ISO Abbreviation:  Eur. J. Nucl. Med. Mol. Imaging     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-17     Completed Date:  2007-10-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101140988     Medline TA:  Eur J Nucl Med Mol Imaging     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  900-9     Citation Subset:  IM    
Affiliation:
Department of Nuclear Medicine, University Hospital, Westfälische Wilhelms-University Münster, Münster, Germany. stegger@uni-muenster.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Algorithms
Elasticity
Female
Gated Blood-Pool Imaging
Heart Ventricles / pathology,  radionuclide imaging*
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging / methods
Male
Middle Aged
Radiopharmaceuticals / diagnostic use*
Technetium Tc 99m Sestamibi / diagnostic use*
Tomography, Emission-Computed, Single-Photon / instrumentation,  methods*
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 109581-73-9/Technetium Tc 99m Sestamibi

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Photo-induced cold vapor generation with low molecular weight alcohol, aldehyde, or carboxylic acid ...
Next Document:  Denitrification in a binary culture and thiocyanate metabolism in Thiohalophilus thiocyanoxidans gen...