| Quantification of left ventricular volume and global function using a fast automated segmentation tool: validation in a clinical setting. | |
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MedLine Citation:
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PMID: 22850929 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Real-time 3D echocardiography (RT3DE) has already been shown to be an accurate tool for left ventricular (LV) volume assessment. However, LV border detection in RT3DE remains a time-consuming task jeopardizing the application of this modality in routine practice. We have recently developed a 3D automated segmentation framework (BEAS) able to capture the LV morphology in real-time. The goal of this study was to assess the accuracy of this approach in extracting volumetric parameters in a clinical setting. 24 RT3DE exams were acquired in a group of healthy volunteers (# = 5) and diseased patients (# = 19), with LV volume/function within a range typically measured in a clinical setting. End-diastolic and end-systolic volumes (EDV, ESV) were manually contoured by 3 expert sonographers from which the stroke volume and ejection fraction (SV, EF) were calculated. The values extracted with BEAS were compared to the average of the 3 experts measurements using correlation and Bland-Altman statistics. Linear regression analysis showed a strong correlation between the automated algorithm and the reference values (R = 0.963, 0.947, 0.944 and 0.853 for EDV, ESV, SV and EF respectively). Bland-Altman analysis revealed a bias (limits of agreement) of 2.59 (-25.39, 30.57) ml, -2.11 (-24.91, 20.69) ml, 4.70 (12.93, 22.34) ml and 3.45 (-8.96, 15.87) %, for EDV, ESV, SV and EF respectively. Total analysis time using BEAS was 30.7 ± 7.5 s. BEAS allows for a fast and accurate quantification of 3D cardiac volumes and global function with minimal user input. It may therefore contribute to the integration of 3D echocardiography in routine clinical practice. |
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Authors:
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Daniel Barbosa; Brecht Heyde; Thomas Dietenbeck; Helene Houle; Denis Friboulet; Olivier Bernard; Jan D'hooge |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-1 |
Journal Detail:
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Title: The international journal of cardiovascular imaging Volume: - ISSN: 1875-8312 ISO Abbreviation: Int J Cardiovasc Imaging Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100969716 Medline TA: Int J Cardiovasc Imaging Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Laboratory on Cardiovascular Imaging & Dynamics, Department of Cardiovascular Sciences, KU Leuven, Herestraat 49, bus 7003, 3000, Leuven, Belgium, daniel.barbosa@uzleuven.be. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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