Document Detail


Quantification of left ventricular volume and global function using a fast automated segmentation tool: validation in a clinical setting.
MedLine Citation:
PMID:  22850929     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Real-time 3D echocardiography (RT3DE) has already been shown to be an accurate tool for left ventricular (LV) volume assessment. However, LV border detection in RT3DE remains a time-consuming task jeopardizing the application of this modality in routine practice. We have recently developed a 3D automated segmentation framework (BEAS) able to capture the LV morphology in real-time. The goal of this study was to assess the accuracy of this approach in extracting volumetric parameters in a clinical setting. 24 RT3DE exams were acquired in a group of healthy volunteers (# = 5) and diseased patients (# = 19), with LV volume/function within a range typically measured in a clinical setting. End-diastolic and end-systolic volumes (EDV, ESV) were manually contoured by 3 expert sonographers from which the stroke volume and ejection fraction (SV, EF) were calculated. The values extracted with BEAS were compared to the average of the 3 experts measurements using correlation and Bland-Altman statistics. Linear regression analysis showed a strong correlation between the automated algorithm and the reference values (R = 0.963, 0.947, 0.944 and 0.853 for EDV, ESV, SV and EF respectively). Bland-Altman analysis revealed a bias (limits of agreement) of 2.59 (-25.39, 30.57) ml, -2.11 (-24.91, 20.69) ml, 4.70 (12.93, 22.34) ml and 3.45 (-8.96, 15.87) %, for EDV, ESV, SV and EF respectively. Total analysis time using BEAS was 30.7 ± 7.5 s. BEAS allows for a fast and accurate quantification of 3D cardiac volumes and global function with minimal user input. It may therefore contribute to the integration of 3D echocardiography in routine clinical practice.
Authors:
Daniel Barbosa; Brecht Heyde; Thomas Dietenbeck; Helene Houle; Denis Friboulet; Olivier Bernard; Jan D'hooge
Related Documents :
12810089 - Increased severity of reperfusion arrhythmias in mouse hearts lacking histamine h3-rece...
2609049 - Assessing antiarrhythmic drug efficacy: multivariate considerations.
1918719 - Arrhythmias induced by device antitachycardia therapy due to diagnostic nonspecificity.
1091129 - Electrophysiology and pharmacology of cardiac arrhythmias. vi. cardiac effects of verap...
20930959 - A review of the mechanisms of ventricular arrhythmia in brugada syndrome.
2066839 - Ventricular arrhythmias in children with an apparently normal heart.
16305859 - Incomplete revascularization during opcab surgery is associated with reduced mid-term e...
2582379 - Electrophysiologic study of tachycardia-dependent paroxysmal his bundle block in man.
1644079 - Heart rate behaviour at different stages of congestive heart failure.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-1
Journal Detail:
Title:  The international journal of cardiovascular imaging     Volume:  -     ISSN:  1875-8312     ISO Abbreviation:  Int J Cardiovasc Imaging     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100969716     Medline TA:  Int J Cardiovasc Imaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Laboratory on Cardiovascular Imaging & Dynamics, Department of Cardiovascular Sciences, KU Leuven, Herestraat 49, bus 7003, 3000, Leuven, Belgium, daniel.barbosa@uzleuven.be.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Synthesis and preliminary biological evaluation of carba analogues from Neisseria meningitidis A cap...
Next Document:  Capability of three-dimensional speckle tracking radial strain for identification of patients with c...