Document Detail

Quantification of duodenogastric reflux in gastroduodenal peptic ulcer and in gastric operation patients, using a 24-h gastric pH measurement as a quantification technique.
MedLine Citation:
PMID:  2340394     Owner:  NLM     Status:  MEDLINE    
Twenty-four-hour gastric pH measurement was used to study duodenogastric reflux. To differentiate between gastric hyposecretion and duodenogastric reflux, we also measured bile acid concentrations in the gastric juice, and regarded pH increases to above 4 as possible episodes of reflux. The procedure was used in 60 patients, divided into the following groups: (1) control group (ten patients); (2) duodenal ulcer (ten patients); (3) type 1 gastric ulcer (five patients); (4) type 3 gastric ulcer (five patients); (5) bilateral truncal vagotomy plus pyloroplasty (ten patients); (6) truncal vagotomy plus Billroth I partial gastrectomy (ten patients); and (7) truncal vagotomy plus Billroth II partial gastrectomy (ten patients). The amount of reflux (areas of pH greater than 4) in the type 1 gastric ulcer and Billroth I and Billroth II groups was significantly greater than that found in the control, duodenal ulcer, type 3 gastric ulcer and truncal vagotomy plus pyloroplasty groups. The mean concentration of total bile acids was also greater in the gastrectomized patients than in the rest of the groups studied. In the type 1 gastric ulcer group the mean bile acid concentration was similar to that of the control group.
R Robles Campos; P Parrilla Paricio; J A Luján Mompeán; J L Aguayo Albasini; F Sánchez Bueno; J M Rodríguez González; L F Martínez de Haro
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  77     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-06-25     Completed Date:  1990-06-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  428-31     Citation Subset:  AIM; IM    
Department of General Surgery, Virgen de la Arrixaca Hospital, University of Murcia, Spain.
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MeSH Terms
Bile Acids and Salts / analysis
Duodenal Ulcer / physiopathology*
Duodenogastric Reflux / diagnosis*
Gastric Acidity Determination
Hydrogen-Ion Concentration
Pylorus / surgery
Stomach / surgery
Stomach Ulcer / physiopathology*
Reg. No./Substance:
0/Bile Acids and Salts

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