| Quantification of chemical vapors in chemosensory research. | |
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MedLine Citation:
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PMID: 12907584 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Studies of olfaction and chemesthesis often rely on nominal, liquid-phase dilutions to quantify the chemicals tested, even though the associated vapor concentrations constitute the actual stimuli. For more than a decade now, our systematic studies of the olfactory and chemesthetic potency of members of homologous chemical series have routinely included quantification of vapors via gas chromatography. This article depicts the relationships between liquid- and vapor-phase concentrations for 60 volatile organic compounds and summarizes the theoretical and technical factors influencing these relationships. The data presented will allow other investigators working with these materials to express them as vapor concentrations even when they lack the resources to perform the analytical measurements. The paper represents a step toward creation of a practical archive for vapor quantification in chemosensory science. |
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Authors:
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J Enrique Cometto-Muñiz; William S Cain; Michael H Abraham |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Chemical senses Volume: 28 ISSN: 0379-864X ISO Abbreviation: Chem. Senses Publication Date: 2003 Jul |
Date Detail:
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Created Date: 2003-08-08 Completed Date: 2004-07-09 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 8217190 Medline TA: Chem Senses Country: England |
Other Details:
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Languages: eng Pagination: 467-77 Citation Subset: IM |
Affiliation:
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Chemosensory Perception Laboratory, Department of Surgery (Otolaryngology), University of California, San Diego, La Jolla, CA 92093-0957, USA. ecometto@ucsd.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Calibration Chemistry Techniques, Analytical Chromatography, Gas / methods Gases / analysis*, chemistry Irritants / analysis*, chemistry Laboratory Chemicals / analysis, chemistry Research Smell* Solutions / chemistry Solvents / chemistry Volatilization |
| Grant Support | |
ID/Acronym/Agency:
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R01 DC02741/DC/NIDCD NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Gases; 0/Irritants; 0/Laboratory Chemicals; 0/Solutions; 0/Solvents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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