Document Detail

Quality of red blood cells using autotransfusion devices: a comparative analysis.
MedLine Citation:
PMID:  12680493     Owner:  NLM     Status:  MEDLINE    
Cell salvage devices are routinely used to process and wash red blood cells (RBCs) shed during surgical interventions. Although the principle theory of cell saving is the same, the actual process to achieve this is very different from one device to another. The purpose of this study was to compare the quality of washed, concentrated RBC produced by five very different cell-saving devices, specifically the Cobe BRAT 2, Medtronic Sequestra 1000, Haemonetics Cell Saver 5, Medtronic Autolog, and the Fresenius CATS. Reservoir and washed red blood cells were analyzed for hematocrit (Hct), platelets (PLT), leukocytes (WBC), potassium (K+), heparin, plasma-free hemoglobin (PFH), RBC mass recovery and recovery rate. The Haemonetics and BRAT 2 had the highest RBC recovery. All devices adequately removed heparin and potassium. The Medtronic Autolog had the highest removal of platelets and PFH; whereas, the BRAT had the lowest. Although the Autolog had the highest leukocyte removal, leukocytes were not adequately washed out by any of the autotransfusion devices. In conclusion, although all cell-saving devices use the same theory of centrifugation, the actual quality of the washed RBC product differs widely from one device to another.
Cyril J Serrick; Mary Scholz; Arthur Melo; Onkar Singh; Dionne Noel
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  The Journal of extra-corporeal technology     Volume:  35     ISSN:  0022-1058     ISO Abbreviation:  J Extra Corpor Technol     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-04-08     Completed Date:  2003-04-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0267637     Medline TA:  J Extra Corpor Technol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  28-34     Citation Subset:  T    
Trillium Health Centre, Mississauga, Ontario, Canada.
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MeSH Terms
Blood Component Removal / instrumentation*
Blood Loss, Surgical
Blood Platelets
Blood Transfusion, Autologous / instrumentation*
Erythrocytes / cytology*
Leukocyte Count
Quality Control
Surgical Equipment / standards*
Surgical Procedures, Operative
Technology Assessment, Biomedical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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