Document Detail

Quality of life in patients with larygeal/hypopharyngeal cancer following total/partial laryngectomy.
MedLine Citation:
PMID:  22926365     Owner:  NLM     Status:  MEDLINE    
AIM: To estimate the quality of life (QOL) of patients with carcinoma of larynx/hypopharynx using the EORTC QLQ-C30 and QLQ-H and N35 questionnaires in relation to the reference values (RV), total (TL) / partial (PL) laryngectomy/ pharyngectomy, combined treatment (surgery, radiotherapy, chemotherapy) (CT) and the time elapsed since surgery.
METHODS: The questionnaires were answered by 45 patients in the first 6 months of 2011. Sixteen (35.6%) patients had PL and 29 (64.4%) TL. Postoperatively, CT was performed in 34 (75.6%) patients (group A), and 11 (24.4%) patients (group B) only had surgery. The time elapsed from surgery of ≤12 months was found in 11 (24.4%) patients in the group A1, and 34 (75.6%) of more than 12 months in the group B1. Comparison was made between all scales of the questionnaires, global (GS), functional (FS) and general symptomatic (GSS) QLQ-C30 and specific symptomatic scale (SSS) QLQ-H and N35.
RESULTS: Comparing our results from all scales of both questionnaires with RV there was no statistically significant differences, except for SSS relating to speech problems (p=0.052574). Comparing PL and TL there was a decrease in FS (p=0.025517) and increased problems with speech, swallowing, sensation, coughing and social contact in SSS (p=0.017595) in TL. Comparing A and B groups, there was a decrease in FS (p=0.00531) increase of all symptoms in GSS (p=0.043388) and SSS (p=0.0505385) in the A group. Comparing A1 and B1 groups better FS (p=0.042271) was registered in A1.
CONCLUSION: Quality of life of our patients is not significantly different from the QOL of similar patients in the world. Comparing all groups, QLQ-C30 and QLQ-H and N35 showed us clear differences in QOL and their clinical use is justified.
Marijana Filipovska-Mušanović; Denad Hodžić; Nermin Hrnčić; Haris Hatibović
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina     Volume:  9     ISSN:  1840-0132     ISO Abbreviation:  Med Glas (Zenica)     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-08-28     Completed Date:  2012-11-01     Revised Date:  2013-02-04    
Medline Journal Info:
Nlm Unique ID:  101250177     Medline TA:  Med Glas (Zenica)     Country:  Bosnia and Hercegovina    
Other Details:
Languages:  eng     Pagination:  287-92     Citation Subset:  IM    
Health Care Centre with Outpatient Clinic, Kakanj, Bosnia and Herzegovina.
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MeSH Terms
Hypopharyngeal Neoplasms / surgery*
Laryngeal Neoplasms / surgery*
Laryngectomy* / adverse effects
Middle Aged
Quality of Life*

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