| Quality-of-life in a long-term multicentre trial in chronic nonspecific lung disease: assessment at baseline. The Dutch CNSLD Study Group. | |
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MedLine Citation:
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PMID: 8112442 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Quality-of-life (QOL) in patients with respiratory illness is a topic of increasing interest to clinicians and researchers. In a multicentre trial, which studies the long-term effects of three medication regimens (beta-agonist plus either placebo, anticholinergic agent or corticosteroid, all by inhalation) in patients with chronic nonspecific lung disease ((CNSLD): asthma and chronic obstructive pulmonary disease (COPD)), quality-of-life was included as an additional outcome measure. We wanted to provide a baseline assessment of quality-of-life in 274 adult patients with a mild to moderate degree of CNSLD. Quality-of-life was measured using a set of six standardized tests: Anxiety, Depression and Sleep Disorders, Optimism and Stigma, and Activities of Daily Living were assessed via scales with adequate validity and reliability, as established in previous work in Dutch patients with CNSLD. We found that quality-of-life was mildly impaired in these patients. Although differences with a reference group were present throughout, these were not significant, probably due to selection of relatively young, clinically stable, and highly motivated patients for our study. Quality-of-life scores showed higher correlation coefficients (0.20 < r < 0.38) to symptom scores than did results of pulmonary function tests (r < 0.015). In logistic regression models, absence from work and hospitalizations due to CNSLD were partly determined by quality-of-life scores.(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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A A Kaptein; P L Brand; F W Dekker; H A Kerstjens; D S Postma; H J Sluiter |
Publication Detail:
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Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The European respiratory journal Volume: 6 ISSN: 0903-1936 ISO Abbreviation: Eur. Respir. J. Publication Date: 1993 Nov |
Date Detail:
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Created Date: 1994-03-28 Completed Date: 1994-03-28 Revised Date: 2013-05-23 |
Medline Journal Info:
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Nlm Unique ID: 8803460 Medline TA: Eur Respir J Country: DENMARK |
Other Details:
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Languages: eng Pagination: 1479-84 Citation Subset: IM |
Affiliation:
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Dept of Psychiatry, Leiden University, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Activities of Daily Living Adolescent Adult Anxiety Asthma / complications, psychology* Chronic Disease Depression / etiology Female Humans Lung Diseases, Obstructive / complications, psychology* Male Middle Aged Quality of Life* Sleep Disorders / etiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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