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Quality of life in Dukes' B and C colorectal carcinoma.
MedLine Citation:
PMID:  21590116     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Adjuvant chemotherapy (ACT) is standard therapy in Dukes' C colorectal carcinoma (CRC) in several countries. Several studies have documented a significant improvement in overall survival, but the clinical efficacy on quality of life (QoL) has been doubted. To clarify this item, we performed a study on QoL in 94 CRC patients diagnosed between 1993-96 and randomised to surgery with or without ACT. 82 'survivors' were mailed the EORTC QLQ C-30. Sixty-two patients (76%) responded. They reported a high level of functioning and a low frequency of symptoms. ACT did not improve global QoL, and tended to cause less pain (p=0.023) and more nausea/vomiting (p=0.065).
Authors:
J Norum; B Vonen; A Revhaug
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oncology reports     Volume:  4     ISSN:  1021-335X     ISO Abbreviation:  Oncol. Rep.     Publication Date:    1997 May-Jun
Date Detail:
Created Date:  2011-05-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9422756     Medline TA:  Oncol Rep     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  645-8     Citation Subset:  -    
Affiliation:
UNIV TROMSO HOSP,DEPT SURG,N-9038 TROMSO,NORWAY.
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