Document Detail

Quality of life before and after proctocolectomy and IPAA in patients with ulcerative proctocolitis--a prospective study.
MedLine Citation:
PMID:  12780909     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The principal aim of the present investigation was to study the general QoL and disease-specific adjustment before, and one-year after, operation with an ileal pouch anal-anastomosis (IPAA) in a consecutive series of patients with ulcerative colitis (UC). PATIENTS AND METHOD: Eleven patients were medically treated and 31 patients underwent colectomy with ileostomy. The patients were interviewed before the IPAA operation and again one-year after closure of the covering loop ileostomy. General quality of life was estimated with a Swedish instrument (according to Kajandi, score range 16-96) and a VA-scale. The instrument for disease-specific adjustment contained specific questions with five factors (score range 34-204). Open questions about quality of life were used to identify areas of concern, which were not included in the other instruments. Postoperative function was described in terms of a functional score (score range 0-15). RESULTS: The results of the general quality of life assessments did not differ significantly when comparing pre-operative to postoperative values. Disease-specific adjustment showed that the medically treated patients had a score of 162; interquartile range (IQR) 145-176. The patients with ileostomy scored 164; IQR 141-180. Postoperatively there was a statistically significant improvement in both groups to 189 (IQR 172-199), an increase of 15%. The open questions revealed restrictions in daily life for both patient groups pre-operatively with improvements after IPAA. The median grading of functional outcome according to the score system was 2. The most frequent problems were: patients who had occasional bowel movements at night, 40%; intermittent perianal soreness, 51%; antidiarrhoeal medication use, 61%. CONCLUSION: General QoL did not change after IPAA. The bowel-specific adjustment in most factors improved in the majority of patients after IPAA. However, half of the IPAA patients had occasional bowel movements at night perianal soreness, and used antidiarrhoeal medication.
I Berndtsson; T Oresland
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland     Volume:  5     ISSN:  1462-8910     ISO Abbreviation:  Colorectal Dis     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-06-03     Completed Date:  2003-08-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100883611     Medline TA:  Colorectal Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  173-9     Citation Subset:  IM    
Institute for Surgical Science, Sahlgrenska University Hospital/Ostra, Göteborg, Sweden.
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MeSH Terms
Anastomosis, Surgical / methods*
Colitis, Ulcerative / surgery*
Colonic Pouches* / adverse effects*
Health Status Indicators
Middle Aged
Postoperative Complications
Proctocolectomy, Restorative / methods*
Prospective Studies
Quality of Life*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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