Document Detail

Quality control measures for cervical cytology laboratories.
MedLine Citation:
PMID:  3287817     Owner:  NLM     Status:  MEDLINE    
The results of three quality control measures for evaluating a cytopathology laboratory's performance in the diagnosis of cervical abnormalities are presented. The sensitivities of cervical cytology were estimated to be 95.5% or 93.1% (using two different methods of analysis) for the detection of histologically diagnosed invasive squamous cell carcinoma of the cervix and 60% for the detection of adenocarcinoma and adenosquamous carcinoma of the cervix in 1983. The positive predictive values for a histologic diagnosis of neoplasia after cytologic reports of CIN III and invasive carcinoma were 92.5% and 99%, respectively. Repeatability of a negative cytologic result exceeded 98%. These results indicate that accurate cervical cytologic reporting can be achieved. Regular monitoring of the type described, which is both practical and reasonably comprehensive, is recommended for all laboratories.
H Mitchell; G Medley; M Drake
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta cytologica     Volume:  32     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1988 May-Jun
Date Detail:
Created Date:  1988-06-28     Completed Date:  1988-06-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  288-92     Citation Subset:  IM    
Victorian Cytology (Gynaecological) Service (VCGS), Melbourne, Australia.
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MeSH Terms
Adenocarcinoma / diagnosis*
Carcinoma, Squamous Cell / diagnosis*
Cytological Techniques / standards*
False Negative Reactions
Predictive Value of Tests
Quality Control
Uterine Cervical Neoplasms / diagnosis*

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