| A Quality Use of Medicines program for general practitioners and older people: a cluster randomised controlled trial. | |
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MedLine Citation:
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PMID: 17605699 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate the effectiveness of an educational Quality Use of Medicines program, delivered at the level of general practice, on medicines use, falls and quality of life in people aged > or = 65 years. DESIGN: Cluster randomised controlled trial conducted in 2002. SETTING: General practices in the Hunter Region, New South Wales, Australia. PARTICIPANTS: Twenty general practitioners recruited 849 patients to participate in the study. INTERVENTION: Education (academic detailing, provision of prescribing information and feedback); medication risk assessment; facilitation of medication review; financial incentives. MAIN OUTCOME MEASURES: Primary measures: a composite score reflecting use of benzodiazepines, non-steroidal anti-inflammatory drugs (NSAIDs) and thiazide diuretics; secondary measures: use of medication reviews, occurrence of falls, quality of life (as assessed by SF-12 and EQ-5D survey scores. RESULTS: Compared with the control group, participants in the intervention group had increased odds of having an improved medication use composite score (odds ratio [OR], 1.86; 95% CI, 1.21-2.85) at 4-month follow-up but not at 12 months. At 4-month follow-up, the intervention group had reduced odds of using NSAIDs (OR, 0.62; 95% CI, 0.39-0.99) and showed a non-significant reduction in use of benzodiazepines (OR, 0.51; 95% CI, 0.20-1.30) and thiazide diuretics (OR, 0.70; 95% CI, 0.48-1.01). Changes in drug use were not significant at 12-month follow-up. At 12 months, intervention-group participants had lower adjusted ORs (AORs) for having a fall (AOR, 0.61; 95% CI, 0.41-0.91), injury (AOR, 0.56; 95% CI, 0.32-0.96), and injury requiring medical attention (AOR, 0.46; 95% CI, 0.30-0.70). Quality-of-life scores were unaffected by the intervention. CONCLUSION: Education and systems for medication review conducted by GPs can be used to improve use of medicines. These interventions are associated with a reduction in falls among older people, without adverse effects on quality of life. |
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Authors:
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Sabrina W Pit; Julie E Byles; David A Henry; Lucy Holt; Vibeke Hansen; Deborah A Bowman |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Medical journal of Australia Volume: 187 ISSN: 0025-729X ISO Abbreviation: Med. J. Aust. Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-07-03 Completed Date: 2007-07-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0400714 Medline TA: Med J Aust Country: Australia |
Other Details:
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Languages: eng Pagination: 23-30 Citation Subset: IM |
Affiliation:
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School of Medical Practice and Public Health, Faculty of Health, University of Newcastle, Newcastle, New South Wales, Australia. sabrina.pit@newcastle.edu.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Accidental Falls
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statistics & numerical data Aged Cluster Analysis Drug Utilization Review / organization & administration* Family Practice / education* Follow-Up Studies Geriatric Assessment / methods* Humans New South Wales Pharmacology, Clinical / education* Program Evaluation Quality of Life |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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