Document Detail


Qualitative haemodynamic validation of a percutaneous temporary aortic valve: a proof of concept study.
MedLine Citation:
PMID:  21231828     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The concept of temporary aortic valves has been suggested in the clinical settings of acute aortic regurgitation and transcatheter aortic valve replacement procedure (TAVR). In TAVR, suggestions have been made to pre-treat or remove the diseased aortic valve prior to implantation of the replacement valve. A successful temporary aortic valve must demonstrate the ability to prevent life-threatening haemodynamics of massive aortic regurgitation. A novel temporary aortic valve (TAV) design, comprised of inflatable balloon elements as a check-valve, can readily be deployed and retrieved via a catheter-system. A simple flow model is set up to test the TAV's performance in severe aortic regurgitation. With induced aortic regurgitation, placement of the TAV is found to increase the distal aortic diastolic pressure, to reduce the widened pulse pressure, to protect proximal aorta-left ventricle from diastolic pressure elevation and to reduce the aortic regurgitant volume. In conclusion, continued development of the TAV system can lead to a successful temporary aortic valve to be used in various appropriate clinical settings.
Authors:
P C Ho
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of medical engineering & technology     Volume:  35     ISSN:  1464-522X     ISO Abbreviation:  J Med Eng Technol     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7702125     Medline TA:  J Med Eng Technol     Country:  England    
Other Details:
Languages:  eng     Pagination:  115-20     Citation Subset:  IM    
Affiliation:
HOCOR Cardiovascular Technologies, LLC, 88 Piikoi Street, Suite 3903, Honolulu, HI 96814, USA. paul.c.ho@hocorcardiovascular.com
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