Document Detail

Quadriceps strengthening exercises are effective in improving pain, function and quality of life in patients with osteoarthritis of the knee.
Jump to Full Text
MedLine Citation:
PMID:  24453599     Owner:  NLM     Status:  PubMed-not-MEDLINE    
OBJECTIVE: The purpose of this research was to verify the effectiveness of an eight-week quadriceps strengthening program on pain, function and quality of life of patients with knee osteoarthritis.
METHODS: A HUNDRED PATIENTS WERE RANDOMIZED INTO TWO GROUPS: 1- Exercise Group (ExG) and 2- Orientation Group. The Timed Up and Go (TUG) test, the Numerical Rating Scale (NRS) and the Short Form-36 were used for the assessment.
RESULTS: Eighty-one patients completed the survey. According to the intention to treat (ITT) analysis, there was statistically significant difference in ExG compared to OG in all the variables assessed.
CONCLUSION: The program quadriceps strengthening exercises applied in this randomized clinical trial was effective in improving pain, function and quality of life of patients with knee osteoarthritis. Level of Evidence I, Randomized Clinical Trial.
Aline Mizusaki Imoto; Maria Stella Peccin; Virgínia Fernandes Moça Trevisani
Related Documents :
18094829 - Spatial distribution by canistropsis microps (e. morren ex mez) leme (bromeliaceae: bro...
23367409 - Analysis of muscle fatigue induced by isometric vibration exercise at varying frequencies.
23522499 - Physical fitness, walking performance, and gait in multiple sclerosis.
15710529 - Epidemiology of gastrointestinal nematodes in cattle on traditional, small-scale dairy ...
23499539 - The effects of respiratory muscle training on improvement of the internal and external ...
18611849 - Density-dependent diversification in north american wood warblers.
3796299 - Thermogenic capacity and brown fat in rats exercise-trained by running.
23830129 - Treatment of exercise-induced bronchoconstriction.
22685479 - Evaluation of functional electrical stimulation to assist cycling in four adolescents w...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta ortopedica brasileira     Volume:  20     ISSN:  1413-7852     ISO Abbreviation:  Acta Ortop Bras     Publication Date:  2012  
Date Detail:
Created Date:  2014-01-23     Completed Date:  2014-01-23     Revised Date:  2014-01-27    
Medline Journal Info:
Nlm Unique ID:  9804509     Medline TA:  Acta Ortop Bras     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  174-9     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): Acta Ortop Bras
Journal ID (iso-abbrev): Acta Ortop Bras
Journal ID (publisher-id): Acta ortop. bras.
ISSN: 1413-7852
ISSN: 1809-4406
Publisher: Sociedade Brasileira de Ortopedia e Traumatologia Regional de São Paulo
Article Information
Download PDF
Received Day: 09 Month: 10 Year: 2011
Accepted Day: 19 Month: 12 Year: 2011
Print publication date: Year: 2012
Volume: 20 Issue: 3
First Page: 174 Last Page: 179
PubMed Id: 24453599
ID: 3718434
DOI: 10.1590/S1413-78522012000300008

Quadriceps strengthening exercises are effective in improving pain, function and quality of life in patients with osteoarthritis of the knee
Aline Mizusaki Imoto
Maria Stella Peccin
Virgínia Fernandes Moça Trevisani
Department of Internal and Therapeutic Medicine of the Universidade Federal de São Paulo (Unifesp)
Correspondence: Mailing address: Rua Pedro de Toledo, 598 Vila Clementino. São Paulo, SP, Brazil. CEP: 04039-001. Email:


Osteoarthritis (OA) is a chronic disease, located in the joints, affecting one third of adults and presenting a tendency to increase with age.1 Knee OA can be associated with symptoms of pain, instability, reduction of range of motion (ROM) and consequently, deterioration in quality of life and function. This functional limitation results in an increase of the risk of morbidity and mortality.2,3

Authors report that patients with knee OA present less quadriceps muscle strength in comparison to the control group. As the quadriceps muscle plays the role of shock absorber, a weakness of this muscle decreases the joint protection, resulting in greater stress and overload on the knee.4 Quadriceps strengthening exercises performed over eight weeks proved just as effective in function improvement as the use of non-hormonal anti-inflammatory drugs in patients with OA of the knee.5 Moreover, moderate-intensity exercises showed themselves to be a good form of treatment not only for the improvement of symptoms, but also in the increase of the glycosaminoglycan content.6

Fransen and McConnell7 carried out a systematic review of the effectiveness of exercises in patients with knee OA. The authors verified that these have a beneficial effect on pain and function. However, there was accentuated variability in terms of the type of exercise evaluated and particularly in relation to the methodological aspects. Besides the physical benefits, the exercises also had a beneficial effect on the mental health of patients with knee OA. Thus, due to the fact that reduced mobility is one of the main factors responsible for limitation of functionality and deterioration of quality of life in patients with knee OA, it is extremely important to conduct research on interventions based on an appropriate methodology, targeting the improvement of the functionality and quality of life of these patients.4 The objective of this randomized clinical trial was to verify the effect of an open kinetic chain quadriceps strengthening exercise program on the pain, function and qualify of patients with knee OA.


The rheumatologists of the Department of Rheumatology of the Ambulatório de Especialidades de Interlagos (Specialty Outpatient Clinic) referred the patients included in the present study. A statistician performed the allocation of the patients using a computer program. Aiming to avoid selection bias, a third person numbered and sealed the opaque envelopes.

All the patients signed a consent term upon joining the group for participation in the study. The patients involved in the survey are registered with the Department of Rheumatology of the Ambulatório de Especialidades de Interlagos - São Paulo, Brazil. The study was conducted over the period between April 2007 and April 2009.

Approval by the Ethics Committee

The Institutional Reasearch Board of Universidade Federal de São Paulo approved this study under the following registration number: CEP 0141/07.

Sample Size

It was estimated that a sample of 40 patients would be able to detect a minimum clinical difference of 1minute ± 3 seconds in the Timed Up and Go (TUG) test, with the power of 80%.8-10 We employed a paired comparison between the three groups with significance level of 0.05 (Student's T-test), using a covariance analysis (ANCOVA). The present study followed the gold standard of evidence in rheumatology, allocating 50 patients in each group.10


One hundred patients were selected according to the inclusion and exclusion criteria established previously. The patients were allocated in two groups:

1) Exercise Group (ExG) (n = 50)

2) Orientation Group (OG) (n = 50).

The inclusion criteria were: age between 50 and 75 years, diagnosis of knee OA according to the criteria of the American College of Rheumatology (ACR) based on history, physical examination and radiographic findings (pain in the knee and one of the following items - over 50 years of age, less than 30min of morning stiffness and crepitation in active movement and osteophytes), knee x-ray in the last 12 months and grade 2 or above in the Kellgren and Lawrence radiographic classification. Patients with a diagnosis of fibromyalgia, unstable heart condition, physical activity more often than twice a week, inability to pedal a stationary bicycle and previous knee arthroplasty were not included. The occurrence of adverse events was considered an exclusion criterion.


The patients' medications were standardized and remained the same during the intervention period. Paracetamol was the drug prescribed for analgesia while diacerein and chloroquine diphosphate were used for control of OA.

Orientation Group (OG)

Patient orientation can be defined as "any educational activity planned with the objective of improving the patient's state of health".11 The patients from the Orientation group received an explanation about the manual after the initial evaluation. The orientation manual (Figure 1) consisted of a description of knee OA, as well as the possible signs and symptoms presented by the patients, and pointed them in the direction of a better way of dealing with the functional difficulties.

Over a period of eight weeks, the patients received two phone calls as a means of encouragement to follow the orientations.

Exercise Group (ExG)

The patients from the ExG group took part in group sessions lasting from 30 to 40 minutes, with a weekly frequency of twice a week.

The load used for muscle strengthening was based on the 10 maximum repetitions test.12 After estimating 100% of the load, 50-60% of this load was established for use in the strengthening of the patients from the study.

The exercise protocol used by us consisted of 10 minutes of warm-up on a stationary bicycle, ischiotibial stretching exercises and three series of 15 repetitions of knee extension exercises, aiming to strengthen the quadriceps muscle. The interval between series was from 30 to 45 seconds. The load used in the exercise was increased according to tolerance. The patient's positioning for the exercise was: seated in a chair, with 90 degrees of knee and hip flexion. The patients from the ExG also received the orientation manual given to the OG group. (Figure 1)


The pre and post-intervention assessments were carried out by a physiotherapist blinded to the patient's group. The following items were evaluated:

Functional performance by means of the TUG test: TUG is a low cost test with a simple method that was developed to assess the patient's functional mobility in everyday activities. This test involves the following sequence of movements: getting out of the chair, walking three meters, turning around and sitting down on the chair again. The time that the patient takes to perform the movement sequence is recorded for comparison before and after treatment.8 In our study, the patients had a chance to become familiar with the test before the collection time was recorded. The best time recorded from three attempts was used. The level of pain was measured using the Numerical Rating Scale from 0 to 10.13 (Figure 2)

Quality of life - we used the SF-36 questionnaire,14 which contains 36 items that assess functional capacity, physical aspects, pain, general state of health, vitality, social aspects, emotional aspects and mental health. The scoring of each item of the questionnaire ranges from 0 to 100, where zero corresponds to the worst general state of health and 100 to the best state of health.14

Statistical Analysis

The paired t-test was used for the assessment between the pre and post-intervention times. Alpha=5% was used in all the tests, and tests with p<0.05 were considered statistically significant. For the intention to treat (ITT) analysis, which includes all the patients who were randomized, we used mixed model variance analysis (ANOVA) with repeated measurements, with measurements of occasion as intragroup factor and intervention as intergroup factor. The relations between observations were analyzed as an unstructured covariance matrix. There was no data input in the ITT to evaluate the pre and post differences between the three groups evaluated, since Chakraborty and Gu15 showed that the mixed model of analysis, without data input, always provides power greater than or equal to the analyses that use the mixed model, with lost data input. In both analyses, the effect size was computed as the difference between the means, divided by the standard deviation, using Cohen's d. The Kruskal-Wallis statistical test was used for comparison between the groups, in relation to the number of days on which analgesic consumption was necessary.


The patients' demographic characteristics in terms of sex, side treated, age, body mass index (BMI), grade of OA according to Kellgren and Lawrence and the values of the initial assessment of NRS, TUG and of the aspects of SF 36 (functional capacity, physical aspects, pain, general state of health, vitality, social aspects, emotional aspects and mental health) are described in Table 1. We can observe the homogeneity of the groups in relation to the demographic characteristics evaluated.

Eighty-one patients (n = 43 in ExG and n = 38 in OG) finished the study. In the ExG group, one patient was excluded due to failure to attend the sessions, while two were instructed to stay at home for a week due to inflammation in the knee. However, the inflammatory state persisted, which made them unable to continue with the exercises of the protocol. Consequently, they did not terminate the protocol and were excluded from the study. One patient had a death in the family (spouse) and declared herself psychologically and socially incapable of continuing with the treatment, two began in a new job and one started treatment nearer his home. In OG, one patient fractured his ankle and 11 did not return for the final assessment even after being contacted by phone. (Figure 2)

Tug test and NRS

ExG presented statistically significant reduction of pain intensity (NRS) (p<0.0001) and in the timing of the TUG test (p<0.0001). (Table 2) OG did not present statistically significant changes in the reduction of the pain level (NRS) or in the TUG test (p>0.05). (Table 2) As regards the comparison between groups, considering the intention to treat analysis, there was statistically significant difference in ExG when compared to OG in the NRS (p=0.00) and TUG (p=0.00) outcome. (Table 3)

SF-36 Questionnaire

In ExG, the evaluation of the items of the SF-36 quality of life questionnaire showed statistically significant improvement in the aspects functional capacity (p<0.001), pain (p=0.00), physical aspects (p=0.00), general state of health (p=0.02) and vitality (p=0.01). (Table 2) There was no statistically significant change in the scores of emotional aspects, mental health and social aspects. (Table 2) The assessments of the patients from OG did not show statistically significant pre and post-intervention difference in the evaluation of the aspects of the SF-36 quality of life questionnaire. In the intergroup comparison, only the functional capacity aspect presented statistically significant difference in ExG when compared to OG (p=0.02). (Table 3)


The present study showed the effectiveness of an exercise protocol for quadriceps strengthening through the evaluation of pain, TUG test and quality of life. It is worth emphasizing that Outcome Measures in Rheumatology recommends the measurement of pain and function as a prerequisite for the assessment of patients with knee, hand and hip OA.16

The rehabilitation protocol applied by us lasted for 8 weeks, in twice-weekly sessions. The quality of life aspects that presented a statistically significant improvement were: functional capacity, physical aspects, pain, vitality and general state of health. Our study is consistent with Aglamis et al.17 who observed a statistically significant pre and post- intervention improvement in the exercise group in the following aspects of SF-36: functional capacity, pain and general state of health.

In the study by Foley et al.,18 the only statistical significant improvement brought about by the strengthening exercises was in the mental aspect of the SF-12 questionnaire, with no statistically significant difference in the score related to physical aspects. The main difference between the study by Foley et al.18 and the present study was the shorter duration of the intervention, which consisted of six weeks. However, both studies performed a rehabilitation protocol that involved 12 or more sessions. According to Fransen and McConnell,7 exercise programs that include more than 12 sessions are associated with an improvement in relation to pain and function.

The focus of the orientation program used in this survey was to advise the patients on how to adjust their daily activities to decrease overload on the knee. The patients were provided with verbal and written guidance, based on the orientation manual distributed to the patients from both groups, which consisted of a brief description of knee OA, as well as the signs, symptoms and possible functional limitations. Moreover, the manual instructed the patients to apply a hot water bottle with the temperature ranging from warm to hot in case of pain with absence of signs of inflammation and use of an ice pack to improve pain when accompanied by swelling. It is worth emphasizing that such guidelines were reinforced during the sessions. The main goal of an orientation program is to maintain or improve health or, in some cases, to decrease the deterioration of the clinical state. However, the orientation group did not present statistically significant improvement in any of the aspects of SF-36 or in the evaluation of pain by means of the numerical rating scale. Nunez et al.19 observed a statistically significant improvement in a group that received guidance in the aspects pain and functional capacity of the SF-36 questionnaire. The main difference between the orientation program of this study and that used by Nunes is the fact that we did not include the exercise instruction as this was not the objective of the present survey. Thomas et al.20 verified that the patients who received only telephone calls as a means of contact intended as guidance and to monitor the symptoms of the patients with knee OA did not present statistically significant reduction in the pain level. On the other hand, the patients who performed exercises at home presented significant decrease in pain, suggesting that the effect of rehabilitation of patients with knee OA is not due to the psychosocial effects but rather to the performance of exercises.

The systematic review carried out by Fransen and McConnel7 on exercises for knee OA verified that only 56% of the studies included performed blind evaluation, 43% used ITT analysis and only 43% executed a blind adequate allocation. The present study considered the methodological aspects to allow the performance of a clinical study of good quality and low risk of bias. To describe this clinical trial, the authors followed the Consort Statement (Consolidated Standards of Reporting Trials), which targets the improvement of quality of ECR articles21.


Quadriceps strengthening exercises included in a rehabilitation program are effective in the improvement of pain, function and quality of life aspects of patients with knee osteoarthritis.


All the authors declare that there is no potential conflict of interest referring to this article.

Study conducted in the Department of Internal and Therapeutic Medicine of the Universidade Federal de São Paulo (Unifesp).

1. Felson DT. Developments in the clinical understanding of osteoarthritisArthritis Res TherYear: 200911120319232065
2. Maurer BT,Stern AG,Kinossian B,Cook KD,Schumacher HR Jr. Osteoarthritis of the knee: isokinetic quadriceps exercise versus an educational interventionArch Phys Med RehabilYear: 199980101293910527090
3. Fidelix TS,Soares BG,Trevisani VF. Diacerein for osteoarthritisCochrane Database Syst RevYear: 20061CD00511716437519
4. Hurley MV. The role of muscle weakness in the pathogenesis of osteoarthritisRheum Dis Clin North AmYear: 19992522839810356418
5. Doi T,Akai M,Fujino K,Iwaya T,Kurosawa H,Hayashi K,et al. Effect of home exercise of quadriceps on knee osteoarthritis compared with nonsteroidal antiinflammatory drugs: a randomized controlled trialAm J Phys Med RehabilYear: 20088742586918356618
6. Roos EM,Dahlberg L. Positive effects of moderate exercise on glycosaminoglycan content in knee cartilage: a four-month, randomized, controlled trial in patients at risk of osteoarthritisArthritis RheumYear: 2005521135071416258919
7. Fransen M,McConnell S. Exercise for osteoarthritis of the kneeCochrane Database Syst RevYear: 20084CD004376 18843657. 18843657
8. Podsiadlo D,Richardson S. The timed "Up & Go": a test of basic functional mobility for frail elderly personsJ Am Geriatr SocYear: 199139214281991946
9. Troosters T,Gosselink R,Decramer M. Six-minute walk test: a valuable test, when properly standardizedPhys TherYear: 2002828826712147012
10. Tugwell P,Shea B,Boers M,Brooks P,Simon Lea. Evidence-based Rheumatology Disponível em:
11. Lorig KR,Mazonson PD,Holman HR. Evidence suggesting that health education for self-management in patients with chronic arthritis has sustained health benefits while reducing health care costsArthritis RheumYear: 1993364439468457219
12. Felício J. Efeito do treinamento aeróbio associado ao treinamento resistido nas variáveis hemodinâmicas, flexibilidade e força em indivíduos hipertensos [monografia]BauruUniversidade Estadual PaulistaYear: 2008
13. Farrar JT,Young JP Jr,LaMoreaux L,Werth JL,Poole RM. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scalePainYear: 20019421495811690728
14. Ciconelli RM,Ferraz MB,Santos W,Meinão I,Quaresma MR. Tradução para a língua portuguesa e validação do questionário genérico de avaliação de qualidade de vida SF-36 (Brasil SF-36)Rev Bras ReumatolYear: 199939314350
15. Chakraborty H,Gu H. Year: 2009A Mixed Model Approach for Intent-to-Treat Analysis in Longitudinal Clinical Trials with Missing Values. RTI Press publication No. MR-0009-0903. Research Triangle Park, NCRTI International Retrieved [date]. Dsponível em:
16. Bellamy N,Kirwan J,Boers M,Brooks P,Strand V,Tugwell P,et al. Recommendations for a core set of outcome measures for future phase III clinical trials in knee, hip, and hand osteoarthritis. Consensus development at OMERACT IIIJ RheumatolYear: 19972447998029101522
17. AglamiŞ B,Toraman NF,Yaman H. Change of quality of life due to exercise training in knee osteoarthritis: SF-36 and WOMACJ Back Musculoskelet RehabilYear: 200922143843-5, 47-8, 4620023363
18. Foley A,Halbert J,Hewitt T,Crotty M. Does hydrotherapy improve strength and physical function in patients with osteoarthritis--a randomised controlled trial comparing a gym based and a hydrotherapy based strengthening programmeAnn Rheum DisYear: 200362121162714644853
19. Nuñez M,Nuñez E,Segur JM,Macule F,Quinto L,Hernandez MV,et al. The effect of an educational program to improve health-related quality of life in patients with osteoarthritis on waiting list for total knee replacement: a randomized studyOsteoarthritis CartilageYear: 20061432798516309929
20. Thomas KS,Muir KR,Doherty M,Jones AC,O'Reilly SC,Bassey EJ. Home based exercise programme for knee pain and knee osteoarthritis: randomised controlled trialBMJYear: 2002325736775212364304
21. Moher D,Hopewell S,Schulz KF,Montori V,Gøtzsche PC,Devereaux PJ,et al. CONSORT 2010 Explanation and Elaboration: Updated guidelines for reporting parallel group randomised trialsJ Clin EpidemiolYear: 2010638e13720346624


[Figure ID: f01]
Figure 1 

Manual for patients with knee osteoarthritis. Caption: ExG- Exercise Group OG – Orientation Group.

[Figure ID: f02]
Figure 2 

Flowchart of the patients over the course of the study.

[TableWrap ID: t01] Table 1 

Demographic characteristics of the patients and baseline value means.

Variable OG ExG p-value
Woman 94.00 90.00 0.76
Man 6.00 10.00  
Side treated +      
Right 34.00 22.00 0.35
Left 41.67 25.00  
Bilateral 22.92 29.17  
Age* 58.78 ±9.60 61.50 ±6.94 0.23
BMI* 30.00 ±5.05 29.72 ±4.11 0.95
KL Grade+     0.83
2 91.18 92.68  
3 5.88 4.88  
4 2.94 2.44  
Pain (NRS)* 6.92 ±2.60 7.42 ±2.01 0.49
Timed up and go test* 10.08 ±2.96 9.34 ±2.47 0.40
Functional Capacity 34.53 ±24.76 31.00 ±19.59 0.66
Physical Aspects 25.60 ±38.39 27.16 ±38.74 0.98
Pain 34.51 ±24.30 34.47 ±18.27 0.83
General State 50.77 ±21.43 52.24 ±27.72 0.23
Vitality 52.53 ±22.08 53.11 ±23.04 0.40
Social Aspects 63.56 ±29.27 71.24 ±26.01 0.42
Emotional Aspects 35.49 ±42.06 47.22 ±46.69 0.46
Mental Health 55.88 ±24.15 59.27 ±24.86 0.08

t01-fn01Caption: OG - Orientation Group; ExG - Exercise Group; BMI - Body Mass Index; NRS - Numerical Rating Scale; SF-36 - Short Form-36 TUG - Timed Up and Go Test; CI - Confidence Interval;.* - Values presented as mean (SD); + - Values presented as percentage.

[TableWrap ID: t02] Table 2 

Results between the pre and post-intervention times.

Variable Groups Pre Post Mean difference (CI of 95%) p-value
Pain (NRS) OG 6.92 ±2.60 5.74    3.14 -0.88 (-1.92;0.15) 0.09
ExG 7.43 ±2.01 4.27    2.45 -3.17 (-4.23;-2.10) <.0001*
TUG OG 10.08 ±2.96 9.22    3.31 -0.57(-1.20;0.06) 0.07
ExG 9.34±2.47 7.42    1.70 -2.00(-2.54;-1.46) <.0001*
Functional Capacity OG 34.53 ±24.76) 41.55    26.66 6.96(-0.46;14.39) 0.06
ExG 31 ±19.59) 49.38    23.94 20.28(12.68; 27.88) <.0001*
Physical Aspects OG 25.6±38.39 39.66    47.49 13.39(-4.59;31.38) 0.13
ExG 27.16±38.74 53.13    46.41 27.85(9.13;46.57) 0.00*
Pain OG 34.51±24.3 44    24.94 6.14 (-5.27;17.55) 0.27
ExG 34.47±18.27 46.98    25.3 16.40 (6.18;26.61) 0.00*
General State of Health OG 50.77±21.43 59.31    22.28 5.89 (-1.34;13.13) 0.10
ExG 52.24±27.72 61.68    25.54 8.05 (1.21;14.89) 0.02*
Vitality OG 52.53±22.08 56.72    23 3.17 (-8.08;14.44) 0.56
ExG 53.11±23.04 63    21.95 10 (2.26;17.73) 0.012*
Social Aspects OG 63.56±29.27 67.76    32.27 0.35(-13.97; 14.69) 0.95
ExG 71.24±26.01 80.73    24.29 9.57(-0.76;19.9) 0.06
Emotional Aspects OG 35.49±42.07 48.31    48.47 13.21 (-10.75;37.18) 0.26
ExG 47.22±46.7 64.18    46.78 16.22(-2.68;35.14) 0.09
Mental Health OG 55.88±24.15 60.41    20.9 1.28(-7.86;10.43) 0.77
ExG 59.27±24.86 64.3    24.35 3.77(-4.31;11.85) 0.35

t02-fn01Caption: OG - Orientation Group; ExG - Exercise Group; NRS - Numerical Rating Scale; CI -Confidence Interval; *Statistically significant result, p≤0.05.

[TableWrap ID: t03] Table 3 

Comparison between groups.

Variable Comparison between groups Difference between the means - CI (95%) Effect size CI (95 %) p-value
Pain (NRS) OG x ExG 2.09 (0.71 ; 3.46) 0.72 (0.24 ; 1.18) 0.00*
TUG OG x ExG 1.29 (0.54 ; 2.04) 0.81 (0.33 ; 1.28) 0.00*
Functional Capacity OG x ExG -12.39 (-23.44; -1.33) 0.72 (0.24; 1.18) 0.02*
Physical Aspects OG x ExG -12.16 (-36.69; 12.37) -0.23 (-0.68; 0.23) 0.32
Pain OG x ExG -4.71 (-21.49; 12.05) -0.16 (-0.61; 0.30) 0.49
General State of Health OG x ExG -1.66 (-11.46; 8.14) -0.08 (-0.53; 0.38) 0.73
Vitality OG x ExG -6.03 (-17.29; 5.22) -0.24 (-0.70; 0.21) 0.29
Social Aspects OG x ExG -6.52 (-21.09; 8.05) -0.20 (-0.59; 0.31) 0.37
Emotional Aspects OG x ExG -3.55 (-30.44; 23.35) -0.07 (-0.52; 0.39) 0.79
Mental Health OG x ExG -1.46 (-12.09; 9.17) -0.06 (-0.52; 0.39) 0.78

t03-fn01Caption: OG - Orientation Group; ExG - Exercise Group; NRS - Numerical Rating Scale; TUG - Timed Up and Go Test; CI - Confidence Interval; * The comparison presented statistically significant difference, p< 0.05.

Article Categories:
  • Original Article

Keywords: Knee, Exercise therapy, Osteoarthritis/rehabilitation, .

Previous Document:  Fractures of the neck of the talus: evaluation of reproducibility of Hawkins' classification.
Next Document:  Correlation between the clinic and the index of cervical myelopathy Torg.