Document Detail


Quadriceps strength is not related to gait impact loading in knee osteoarthritis.
MedLine Citation:
PMID:  20303275     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Joint loading has been implicated in the pathogenesis of knee osteoarthritis (OA). While compartment-specific measures such as the knee adduction moment have received much attention in the literature, less is known about other measures of dynamic loading in this patient population. This cross-sectional study assessed strength and walking patterns of 204 individuals with radiographically confirmed medial tibiofemoral OA and varus malalignment. Pearson product moment correlations and regression analyses were used to determine the bivariate and multivariate relationships amongst measures of impact loading (rate of loading and heelstrike transient occurrence) with demographic, clinical (in particular, radiographic disease severity, lower limb alignment, and self-reported pain and function), and biomechanical variables (maximum voluntary isometric quadriceps strength and gait kinematics). While maximum voluntary isometric quadriceps strength was significantly correlated with rate of loading (r>0.27) when walking at a freely chosen speed, multiple regression analyses indicated that rate of loading was primarily dictated by walking speed (p<0.001), and the effect of quadriceps strength was insignificant when accounting for all other included variables. Individuals who exhibited a heelstrike transient in their vertical ground reaction force profile were significantly more varus malaligned and were more likely to demonstrate severe radiographic degeneration than those who did not exhibit heelstrike transients. These results demonstrate higher impact loading during walking in those with knee OA with faster self-selected walking speeds, though the relationship with quadriceps strength is less clear. Importantly a potential association between disease characteristics, such as malalignment and disease severity, and higher impact loading was also observed.
Authors:
Michael A Hunt; Rana S Hinman; Ben R Metcalf; Boon-Whatt Lim; Tim V Wrigley; Kelly-Ann Bowles; Georgina Kemp; Kim L Bennell
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-03-29
Journal Detail:
Title:  The Knee     Volume:  17     ISSN:  1873-5800     ISO Abbreviation:  Knee     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-06-15     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9430798     Medline TA:  Knee     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  296-302     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier B.V. All rights reserved.
Affiliation:
Centre for Health, Exercise and Sports Medicine, School of Physiotherapy, University of Melbourne: Melbourne, Australia. michael.hunt@ubc.ca
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MeSH Terms
Descriptor/Qualifier:
Aged
Bone Malalignment / physiopathology,  radiography
Cross-Sectional Studies
Female
Gait*
Humans
Knee Joint / physiopathology*,  radiography
Male
Middle Aged
Muscle Contraction / physiology
Muscle Strength / physiology
Osteoarthritis, Knee / physiopathology*,  radiography
Quadriceps Muscle / physiopathology*
Range of Motion, Articular
Severity of Illness Index
Weight-Bearing / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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