Document Detail


QRS changes in direct fetal electrocardiogram during uterine overstimulation; report of four cases.
MedLine Citation:
PMID:  2599259     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Four cases are presented in which increased QRS complex voltages or deviation of the mean electrical axis were observed in the fetus by direct fetal electrocardiogram (ECG) during delivery under anaesthesia. There was transformation of the initial QRS aspect before delivery. These changes were only observed when large doses of oxytocin (20 IU in 500 ml) were used after Pentothal administration in deliveries in which other fetal ECG alterations (bradycardia, ST changes, T inversion) and/or low pH values had been observed. In case 1 there were ST level changes, inversion of the T wave and transformation of the QRS complex from RS to Rs. Case 2 showed a change from RS to QR type complex associated with repolarization defects. In cases 3 and 4, ST level changes, inversion and increased QRS complex voltages were observed. We checked that the modifications observed were not due to changes in position of the fetus during recording. It is thought that the acute redistribution of the fetal blood volume due to oxytocin overstimulation in fetal hearts with hypoxic signs may lead to compensatory mechanisms such as tachycardia, increased contractile activity (higher QRS) and functional predominance of one side of the fetal heart (deviation of the electrical axis) subjected to sudden load.
Authors:
N Carretti; V Palazzuoli; S Mondillo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  33     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-01-30     Completed Date:  1990-01-30     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  281-6     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Siena, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Electrocardiography*
Female
Fetal Hypoxia / chemically induced*,  diagnosis,  physiopathology
Fetal Monitoring
Heart Rate, Fetal / drug effects*
Humans
Labor, Obstetric*
Oxytocin / adverse effects*,  therapeutic use
Pregnancy
Chemical
Reg. No./Substance:
50-56-6/Oxytocin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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